ROS-responsive core–shell microgels for phase-specific treatment …
2025年3月1日 · In this study, SaB/Cand@C-S MGs were introduced. The shell composed of HBPAK scavenges ROS, restoring mitochondrial function and disrupting harmful ROS-induced …
Mitochondrial P-JNK target, SAB (SH3BP5), in regulation of
2024年3月15日 · We discuss here the mechanism and modulators of the JNK-SAB-ROS activation loop, which is the core component of mitochondria-dependent cell death, specifically …
trans -Fatty acids facilitate DNA damage-induced apoptosis
2020年2月17日 · These results demonstrate that in response to DNA damage, TFAs drive the mitochondrial JNK-Sab-ROS positive feedback loop and ultimately apoptosis, which may …
Sab蛋白的研究进展 - 仁和软件
2018年4月2日 · Takeshita等 研究发现, Sab是分泌生物活性肽humanin发挥神经保护作用的下游关键效应分子, humanin可促进Sab蛋白和基因的表达, 而Sab能够直接抑制JNK, 降低p-JNK, 进 …
Mitochondrial P-JNK target, SAB (SH3BP5), in regulation of cell …
2024年3月14日 · We discuss here the mechanism and modulators of the JNK-SAB-ROS activation loop, which is the core component of mitochondria-dependent cell death, specifically …
JNK interaction with Sab mediates ER stress induced inhibition of ...
2014年1月9日 · JNK interacts with Sab, which leads to the inhibition of respiration and ROS production, the latter amplified by calcium release from ER, creating a self-amplification cycle …
反式脂肪酸通过线粒体JNK-Sab-ROS阳性反馈回路促进DNA损伤诱 …
EA的促凋亡作用可通过击倒Sab（一种位于线粒体外膜的c-Jun N端激酶（JNK）相互作用蛋白）来阻断，介导线粒体活性氧（ROS）生成和JNK激活的相互放大。 EA增强了阿霉素诱导的线粒 …
trans-Fatty acids facilitate DNA damage-induced apoptosis
2020年2月17日 · These results demonstrate that in response to DNA damage, TFAs drive the mitochondrial JNK-Sab-ROS positive feedback loop and ultimately apoptosis, which may …
We discuss here the mechanism and modulators of the JNK-SAB-ROS activation loop, which is the core component of mitochondria-dependent cell death, specifically apoptosis and …
The Regulation of JNK Signaling Pathways in Cell Death through …
2018年10月25日 · JNK-SAB-ROS activation loop is an important cell death-promoting pathway in apoptosis and mitochondrial permeability transition pore (MPT)-regulated necrosis (in the …