2024年10月14日 · sacubitril and valsartan lowers the risk of being hospitalized when symptoms get worse and reduces the risk of death from heart failure. Sacubitril and valsartan is also used to treat symptomatic heart failure in children who are at least 1 year old.

2015年9月20日 · Sacubitril and valsartan combination is used to treat chronic heart failure in adults to help reduce the risk of death and hospitalization. This medicine is also used to treat children with symptomatic heart failure. Valsartan is an angiotensin II receptor blocker (ARB).

2024年2月29日 · Differentiate between sacubitril-valsartan and other heart failure therapies regarding the mechanism of action, efficacy, and safety profiles. Assess patient response to sacubitril-valsartan therapy by monitoring symptoms, biomarkers, and adverse events.

2024年9月1日 · Entresto contains sacubitril and valsartan, which each have a different mechanism of action. Sacubitril works by blocking neprilysin, an enzyme that breaks down certain peptides in the body.

Sacubitril/valsartan, sold under the brand name Entresto among others, is a fixed-dose combination medication for use in heart failure. It consists of the neprilysin inhibitor sacubitril and the angiotensin receptor blocker valsartan. The combination is sometimes described as an "angiotensin receptor-neprilysin inhibitor" (ARNi). [9]

2024年3月8日 · Learn about the side effects of sacubitril/valsartan, from common to rare, for consumers and healthcare professionals.

Indicated to reduce risk of cardiovascular death and hospitalization in chronic heart failure (CHF); benefits are most clearly evident in patients with left ventricular ejection fraction (LVEF)...

Entresto is a combination of two medicines, sacubitril and valsartan, which work together to help strengthen your heart’s ability to pump blood and prevent fluid buildup. How is Entresto supplied...

View sacubitril with valsartan information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding, contra-indications and drug action.

Valsartan is in a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently. Sacubitril is in a class of medications called neprilysin inhibitors.