Thermafiber® SAFB™ (Sound Attenuation Fire Blankets) are mineral wool batts that provide sound control and fire protection in wall and floor-ceiling assemblies

2024年12月25日 · SAFB (Scaffold Attachment Factor B) is a Protein Coding gene. Diseases associated with SAFB include Denys-Drash Syndrome and Fanconi Anemia, Complementation Group I. Among its related pathways are Metabolism of proteins and Transport of the SLBP independent Mature mRNA.

该基因编码一种 DNA 结合蛋白，该蛋白对支架或基质附着区域 DNA 元件 (S/MAR DNA) 具有高度特异性。 这种蛋白质被认为与将染色质环的碱基连接到核基质有关，但关于这种蛋白质是染色质的成分还是核基质蛋白，存在相互矛盾的证据。 支架附着因子是特异性结合 S/MAR 的核基质蛋白 (NMP) 的特定子集。 编码的蛋白质被认为是在活跃转录基因附近组装“转录体复合物”的分子基础。 它参与热休克蛋白 27 转录的调节，可作为雌激素受体共阻遏物，是乳腺肿瘤发生的候选物。 …

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2024年3月21日 · 本文通过Direct RNA测序及多种生理生化方法，研究了SAFB蛋白对转座子活性的调控作用及其在进化中的意义，发现SAFB蛋白在调控转座子活性和维护基因组稳定性方面扮演着关键角色，揭示了其内在作用机制与进化压力和环境响应密切相关。

Scaffold attachment factor B, also known as SAFB, is a gene with homologs that have been studied in humans and mice. [5] This gene encodes a DNA-binding protein that has specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA).

The SAFB (scaffold attachment factor B) proteins (SAFB1, SAFB2 and SAFB-like transcriptional modulator, SLTM), which are highly conserved evolutionarily, were first identified on the basis of their ability to bind scaffold attachment region DNA elements, but attention has subsequently shifted to their RNA-binding and protein–protein interactions.

Scaffold attachment factor (SAFB) 1 and its homologue SAFB2 are multifunctional proteins that are involved in various cellular mechanisms, including chromatin organization and transcriptional regulation, and are also corepressors of estrogen receptor alpha (ERα). Both SAFBs are expressed at high lev …

SAFB(scaffold attachment factorB)是一种核基质结合因子,属于一个核蛋白家族,目前共发现3个家族成员,首先发现的是SAFBl,第二个是SAFB2,第三个是SLTM.SAFB结构上有一些重要的功能 …

Scaffold attachment factor B (SAFB) is a conserved RNA-binding protein that is essential for early mammalian development. However, the functions of SAFB in mouse embryonic stem cells (ESCs) have not been characterized. Using RNA immunoprecipitation followed by RNA-seq (RIP-seq), we examined the RNAs …