Sal-like protein 4 (SALL4) is a transcription factor encoded by a member of the Spalt-like (SALL) gene family, SALL4. [5][6] The SALL genes were identified based on their sequence homology …

SALL4 transcription factor is associated with embryonic cell pluripotency and has been shown as a useful immunohistochemical marker for germ cell tumors. However, information of SALL4 …

SALL4 is a stemness marker that regulates pluripotency and sustains the self‐renewal properties of ESCs and HSCs. In human adult tissue, its aberrant expression promotes cancer …

2009年6月4日 · SALL4 is a novel stem cell marker essential to maintain pluripotency and self-renewal of embryonic stem cells. In the current study, the authors investigated the utility of …

2023年6月20日 · SALL4（分裂样蛋白 4）是果蝇同源基因 spalt (sal) 的哺乳动物同源物的成员，作为锌指转录因子控制胚胎干细胞的自我更新和多能性。 SALL4 表达在发育过程中逐渐减 …

2009年12月1日 · Our results indicate that SALL4 is a novel sensitive diagnostic marker for primary germ cell tumors of the CNS with high specificity. SALL4 is a more sensitive marker …

2020年3月3日 · To examine whether sal/SALL4 is able to modulate cell movement in other tissues, we turned to the salivary gland, where sal was endogenously expressed at a …

2015年2月1日 · Gain- and loss-of-function studies reveal that SALL4 regulates proliferation, apoptosis, invasive migration, chemoresistance, and the maintenance of cancer stem cells …

Full gene name according to HGNC. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Assigned HPA protein class (es) for the encoded protein (s). …

2013年1月11日 · During embryo development, Sall4 regulates axis formation and expression was observed in progenitor populations of brain, neural tube, heart, pituitary gland, somites and …

Sall4 is also a causative gene for Okihiro syndrome and is essential for the formation of many organs in both humans and mice. ... Asterisk: ureteric bud; ad: adrenal gland; ov: ovary. Scale …

2025年3月4日 · Spalt-like transcription factor 4 (SALL4) plays a vital role in the progression of many human diseases. However, the role and mechanism of SALL4 regulates in keloid …

General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene …

2009年10月9日 · Our results indicate that SALL4 is a novel sensitive diagnostic marker for primary germ cell tumors of the CNS with high specificity. SALL4 is a more sensitive marker …

2023年6月20日 · The potent roles of SALL4 in regulating cancer cell proliferation, apoptosis, metastasis, and drug resistance have been reported. SALL4 plays a dual role in epigenetic …

Summary of SALL4 (dJ1112F19.1, ZNF797) expression in human tissue. Nuclear expression in spermatogonia and in oocytes.

SALL4 is a dual-mode transcription factor that can activate and repress clusters of genes that are critical for self-renewal and pluripotency. SALL4 performs its repressive role through …

2006年9月17日 · These results demonstrate that Sall4 is a transcriptional activator of Pou5f1 and has a critical role in the maintenance of ES cell pluripotency by modulating Oct4 expression. …

2024年2月13日 · Liu L, Zhang J, Yang X, Fang C, Xu H, Xi X (2015) SALL4 as an Epithelial-Mesenchymal Transition and Drug Resistance Inducer through the Regulation of c-Myc in …

Expression of SALL4 (dJ1112F19.1, ZNF797) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers.