Saporins are so-called ribosome inactivating proteins (RIPs), due to its N-glycosidase activity, from the seeds of Saponaria officinalis (common name: soapwort). It was first described by …

Saporin is a ribosome-inactivating protein that can cause inhibition of protein synthesis and causes cell death when delivered inside a cell. Development of commercial Saporin results in …

Saporin, which is extracted from Saponaria officinalis, is a protein toxin that inactivates ribosomes. Saporin itself is non-selective toxin but acquires high specificity after conjugation with different …

Saporin, a type I ribosome-inactivating protein from soapwort plant, is a potent protein synthesis inhibitor. Catalytically, saporin is a characteristic N-glycosidase, and it depurinates a specific …

2020年2月21日 · Since saporin has poor permeability across the cell membrane, it was encapsulated in a lipid-based nanoparticle system (EC16-1) that effectively delivered the …

2015年1月1日 · Saporin is a ribosome-inactivating protein (RIP) from the common soapwort (Saponaria officinalis L.). It is an enzyme that releases a particular adenine from the 28S …

Saporin (also known as saporin-S6) is a type I RIP isolated from the seeds of Saponaria officinalis. The mature form of saporin is composed of 253 amino acids 19 (Fig. 10.2). Due to …

2013年10月7日 · These immunotoxins have shown many interesting results when used in cancer therapy, particularly in hematological tumors. The high enzymatic activity, stability and …

Saporin-S6 (also known as saporin) is a plant toxin belonging to the ribosome-inactivating protein (RIP) family, a class of toxic enzymes that is widely distributed among plant genera whose …

Saporin, a type I ribosome-inactivating protein from soapwort plant, is a potent protein synthesis inhibitor. Catalytically, saporin is a characteristic N -glycosidase, and it depurinates a specific …