somatic cell nuclear transfer (SCNT), technique in which the nucleus of a somatic (body) cell is transferred to the cytoplasm of an enucleated egg (an egg that has had its own nucleus removed). Once inside the egg, the somatic nucleus is reprogrammed by egg cytoplasmic factors to become a zygote (fertilized egg) nucleus.

In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory strategy for creating a viable embryo from a body cell and an egg cell. The technique consists of taking a denucleated oocyte (egg cell) and implanting a donor nucleus from a somatic (body) cell.

体细胞核移植（Somatic Cell nuclear transfer）: 又称 体细胞克隆 ，作为动物 细胞工程技术 的常用技术手段，即把体细胞核移入 去核 卵母细胞 中，使其发生再程序化并发育为新的胚胎，这个胚胎最终发育为动物个体。

体细胞核移植 （Somatic cell nuclear transfer，简称：SCNT），又称体细胞克隆，是 遗传学 及 发育生物学 实验之中一种使用体细胞和卵细胞培育胚胎的常用技术手段。 该技术提取 去核卵母细胞，并把供体 体细胞核 移入卵母细胞中。 体细胞核移植技术被应用于临床治疗及 克隆技术 中。 世界上第一只克隆哺乳动物 多利羊 即是依靠体细胞核移植技术诞生。 2018年1月， 中国科学院 神经科学研究所非人灵长类平台的研究团队宣布成功通过体细胞核移植技术克隆出两只 食蟹猴 中 …

Matoba and Zhang discuss recent advances in somatic cell nuclear transfer technology, particularly new methods to overcome epigenetic barriers, and highlight the potential applications of this cloning technology for both reproductive efforts and therapy.

Somatic cell nuclear transfer is used primarily for generating cells and tissues that are immunocompatible with the somatic cell donor, a concept known as therapeutic cloning. Originally suggested in 1999, the production of patient-specific or genetically identical embryonic stem cells (ESCs) for research and therapeutic purposes emphasizes the ...

Somatic cell nuclear transfer (SCNT) is a procedure by which a nucleus from a fully differentiated cell (e.g., fibroblast) undergoes complete genetic reprogramming when it is introduced into an enucleated oocyte. The prime advantage of SCNT is the possibility of creating multiple genetically identical animals.

Somatic cell nuclear transfer (SCNT) has a broad spectrum of potential applications, including rescue of endangered species, production of transgenic animals, drug production, and regenerative medicine.

2014年11月4日 · Somatic cell nuclear transfer (SCNT) is a technology applied in cloning, stem cell research, and regenerative medicine. Somatic cells are cells that have gone through the differentiation process and are not germ cells. Somatic cells donate their nuclei, which scientists transplant into eggs after removing their nucleuses (enucleated eggs).

Somatic cell nuclear transplantation (SCNT) and induced pluripotent stem cell (iPSC) technologies can be employed to change cell fate by reprogramming. The discoveries of SCNT and iPSCs were awarded the Nobel Prize for Physiology and Medicine in 2012, which reaffirmed the importance of cell fate pla …