Genetics and pathogenesis of idiopathic scoliosis
2016年11月28日 · Idiopathic scoliosis (IS), the most common form of spinal deformity, affects otherwise healthy children and adolescents during growth. It usually presents as a rib hump visible at forward bending, together with unleveled shoulders and an asymmetrical waist.
Understanding Genetic Factors in Idiopathic Scoliosis, a Complex ...
Several features of the disease including potentially strong genetic effects, the early onset of disease, and standardized diagnostic criteria make IS ideal for genomic approaches to finding risk factors.
Unraveling the Mystery: Is Scoliosis Genetic?
2024年11月7日 · Current research suggests scoliosis is influenced by genetic factors, with genetic mutations playing a significant role in its development. While the exact genetic mechanisms are still under study, genetic predisposition is considered a key factor in understanding the hereditary nature of scoliosis.
Is scoliosis hereditary, genetic, or both?
2020年3月10日 · Research shows scoliosis can be hereditary & run in families, but it can also arise spontaneously. Genetics play an important role in scoliosis development.
Genetics and pathogenesis of scoliosis - PMC
We identify gene groups related to different biological processes and explore multifaceted pathogenesis of idiopathic scoliosis, including evolutionary adaptations to bipedalism and developmental and homeostatic spinal aberrations.
Is Scolioisis Genetic? What The Science Says - Hudson Valley Scoliosis
It is possible scoliosis is inherited from a parent the way other genetic traits are passed down from parent to child. This theory is greatly supported by the tendency for scoliosis to run in families as seen with parent, child and siblings.
Genetics and pathogenesis of scoliosis - ScienceDirect
2024年12月1日 · We identify gene groups related to different biological processes and explore multifaceted pathogenesis of idiopathic scoliosis, including evolutionary adaptations to bipedalism and developmental and homeostatic spinal aberrations.
Genetics and pathogenesis of scoliosis - North American Spine …
2024年9月6日 · This comprehensive review explores the genetic factors and multifaceted pathogenesis of idiopathic and adult degenerative scoliosis, proposing a new model for scoliosis etiopathogenesis and highlighting future research directions.
A New Look at Causal Factors of Idiopathic Scoliosis: Altered ...
The genetic epidemiology of idiopathic scoliosis. European spine journal: official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2012;21:1905–19. doi: 10.1007/s00586-012-2389-6.
Scoliosis Causes: Is Scoliosis Hereditary, Genetic, or Other?
2023年11月29日 · The genetic architecture of scoliosis is possibly polygenic, meaning multiple genes contribute to its onset. This complexity necessitates a nuanced approach to treatment, personalized to the genetic makeup and overall health profile of each patient.