Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is an adverse drug eruption presenting as a distinctive erythematous rash involving the skin folds.

2022年10月3日 · Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), previously known as baboon syndrome, is a symmetrical erythematous rash on the gluteal and intertriginous areas observed after exposure to systemic drugs. This activity reviews the pathogenesis of this condition, the diagnostic criteria, and the most common drugs involved.

The diagnostic criteria for SDRIFE include: 1) exposure to a systemically administered drug, either at the first or second administration; 2) sharply demarcated erythema of the gluteal/perianal area and/or V-shaped erythema of the inguinal/perigenital area; 3) involvement of at least one other intertriginous/flexural localization; 4) symmetry ...

Baboon syndrome, also called symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), is an erythematous maculopapular rash that presents in skin folds in a symmetrical pattern. This condition may develop after the patient starts a ...

2021年10月25日 · The pathogenic mechanism of SDRIFE is not well understood, but it is thought to be most likely due to a type IV delayed hypersensitivity immune response. 2 Although SDRIFE is uncommon, cases in the literature document SDRIFE caused by antibiotics, asthma medications, radiocontrast media, chemotherapeutic agents, and biologics. 3

We report a patient with previously unreported symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) with remarkable cutaneous symptoms associated with infliximab treatment for chronic plaque psoriasis.

The symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is a delayed flexural exanthema induced by a systemic drug without previous cutaneous sensitization, typically presenting as “a sharply defined symmetrical erythema of the gluteal area and in the flexural or intertriginous folds without systemic symptoms and signs ...

Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is a rare drug-induced manifestation and presents as an asymptomatic demarcated rash a few days after offending drug administration in the gluteal/inguinal region with involvement of …

2022年8月18日 · Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is a nonimmediate, T-cell–mediated hypersensitivity drug reaction, characterized by symmetrical erythema involving the gluteal and intertriginous areas without systemic involvement.

2022年10月3日 · Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), previously known as baboon syndrome, is a symmetrical erythematous rash on the gluteal and intertriginous areas observed after exposure to systemic drugs. This activity reviews the pathogenesis of this condition, the diagnostic criteria, and the most common drugs involved.