2022年11月10日 · Mechanically, we found that LINC02820 may affect the cytoskeletal remodeling, interact with splice factor 3B subunit 3 (SF3B3), and cooperate with TNFα to …

2024年4月26日 · Our findings revealed that SF3B3 promoted CRC progression and metastasis by regulating mTOR alternative splicing and SREBF1-FASN-mediated lipogenesis, providing …

2022年11月10日 · Considering SF3B3 is a subunit of U2, a small nuclear ribosomal protein, and is involved in the alternative splicing of RNA. Taken together, we conclude that LINC02820 …

Mechanically, we found that LINC02820 may affect the cytoskeletal remodeling, interact with splice factor 3B subunit 3 (SF3B3), and cooperate with TNFα to amplify the NF-κB signaling …

As U2 snRNP enters nuclear pre-mRNA splicing, SF3b plays key roles in recognizing the branch point sequence (BPS) and facilitating spliceosome assembly and activation. Since the …

该基因编码剪接因子 3b 蛋白复合物的第 3 亚基。 剪接因子 3b 与剪接因子 3a 和一个 12S RNA 单元一起形成 U2 小核糖核蛋白复合物 (U2 snRNP) 。 剪接因子 3b/3a 复合物以序列独立的方式 …

The SF3b complex is an intrinsic component of the functional U2 small nuclear ribonucleoprotein (snRNP). As U2 snRNP enters nuclear pre-mRNA splicing, SF3b plays key roles in …

To evaluate the clinical significance of SF3B4 and HOX-L in ESCC patients, we examined SF3B4 and HOX-L mRNA levels in 50 pairs of primary ESCC and adjacent tissues. The results …

Studies have shown that SF3B1, SF3B2, and SF3B3 can regulate target gene expression by alternative splicing to promote cancer progression (Chen et al., 2017), also SF3B3 controls AS …

According to a series of assays, we found that LINC02820 may bind to SF3B3 to function, and can cooperate with TNFα to regulate the NF-κB signaling pathway to work in ESCC (Fig. 8H). …