SGLT-2抑制剂，中文名为钠-葡萄糖协同转运蛋白2 (sodium-dependent glucose transporters 2，SGLT-2)抑制剂，可以抑制肾脏对葡萄糖的重吸收，使过量的葡萄糖从尿液中排出，降低血 …

Sodium-dependent glucose cotransporters (or sodium-glucose linked transporter, SGLT) are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine …

2020年3月2日 · Empaglifolzin, canagliflozin, and dapagliflozin are SGLT2 (sodium-glucose linked transporter type 2) inhibitors for treatment of type 2 diabetes mellitus that also reduce blood …

2023年6月3日 · Sodium-glucose cotransporter 2 (SGLT-2) inhibitors act on the SGLT proteins expressed in the proximal renal convoluted tubules. Four agents (canagliflozin, dapagliflozin, …

2023年5月30日 · SGLT-2 inhibitors are a class of medicine used to lower high blood glucose levels in people with type 2 diabetes. They may also be called gliflozins. SGLT-2 inhibitors …

Because of glucose excretion, these drugs lower plasma glucose and glycosylated hemoglobin levels in patients with type 2 diabetes mellitus. The drugs also protect against heart and renal …

2023年3月16日 · SGLT2 inhibitors were developed to lower blood sugar in type 2 diabetes. But they do have other uses. Some of them are approved for chronic kidney disease. They also …

2021年1月，英国临床糖尿病专家协会(abcd)联合英国糖尿病联合会共同发布了非糖尿病专科医生应用sglt2抑制剂治疗2型糖尿病的建议。钠葡萄糖共转运体2（sglt2）抑制剂是目前公认的治 …

2021年7月16日 · SGLT-2i主要通过抑制肾小管SGLT2，降低肾糖阈，减少尿液中葡萄糖的重吸收，促进尿葡萄糖排泄，从而降低血液循环中葡萄糖的水平。 SGLT-2i作用机制独特，不依赖于 …

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