Positive (i.e., M-Protein present), a serum Immunofixation (sIFE) test is automatically ordered and run (at additional charge). This reflexed test serves to identify the M-protein's heavy and light chain components (e.g., "IgG Kappa").

Detect and identify monoclonal gammopathy (M protein) found on serum protein electrophoresis; diagnose myeloma, macroglobulinemia of Waldenström; evaluate amyloidosis; evaluate lymphoproliferative disease (malignant lymphoma and others) and collagen disease in general; diagnose and characterize immune deficient and dysgammaglobulinemic states.

Immunofixation is used to evaluate monoclonal gammopathy (M protein) found on serum protein electrophoresis; evaluate amyloidosis. Has application to the evaluation of lymphoproliferative …

2019年1月1日 · SIFE is required for confirmation of abnormalities detected by SPEP and to improve detection of monoclonal immunoglobulin not detected by SPEP alone. The sample is applied to a total of six lanes on the gel.

Introduction Serum immunofixation electrophoresis (SIFE) and serum free light chain (SFLC) assay are imperative investigations in diagnosis and follow-up of multiple myeloma (MM). SFLC assays are reported to have higher sensitivity than SIFE. However, discrepancies have been reported between them.

2023年5月5日 · Introduction Serum immunofixation electrophoresis (SIFE) and serum free light chain (SFLC) assay are imperative investigations in diagnosis and follow-up of multiple myeloma (MM). SFLC assays are reported to have higher sensitivity than SIFE. However, discrepancies have been reported between …

Positive (i.e., M-Protein present), a serum Immunofixation (sIFE) test is automatically ordered and run (at additional charge). This reflexed test serves to identify the M-protein's heavy and light chain components (e.g., "IgG Kappa"). This finding …

2016年6月1日 · The reliable detection of paraprotein in serum and urine is the primary purpose of electrophoretic procedures in clinical laboratories. Screening immunofixation electrophoresis (sIFE) employs a single application of antisera directed against heavy and light chains that facilitates the detection of p …

2021年3月8日 · Serum protein electrophoresis (SPEP) and serum protein immunofixation electrophoresis (SIFE) are used routinely for evaluation of serum proteins in general and for diagnosis of monoclonal immunoglobulins in particular.

2020年11月5日 · Diagnostic methods for monoclonal gammopathy are serum protein electrophoresis (SPEP) and serum protein immunofixation electrophoresis (SIFE). The corresponding methods for urine are urine protein electrophoresis (UPEP) and urine protein immunofixation electrophoresis (UIFE).