Sigma-1 receptor - Wikipedia
In humans, the σ 1 receptor is encoded by the SIGMAR1 gene. [6] [7] The σ 1 receptor is a transmembrane protein expressed in many different tissue types. It is particularly concentrated …
SIGMAR1 Gene - GeneCards | SGMR1 Protein | SGMR1 Antibody
2024年12月25日 · SIGMAR1 (Sigma Non-Opioid Intracellular Receptor 1) is a Protein Coding gene. Diseases associated with SIGMAR1 include Neuronopathy, Distal Hereditary Motor, …
Sigmar1's Molecular, Cellular, and Biological Functions in …
2021年7月7日 · The Sigma 1 receptor (Sigmar1) is a ubiquitously expressed multifunctional inter-organelle signaling chaperone protein playing a diverse role in cellular survival. Recessive …
西格玛非阿片类细胞内受体 1（SIGMAR1）基因 | MCE
正如其之前的名称阿片受体 sigma 1 (OPRS1) 所示，该基因的产物被错误地认为具有阿片受体的功能；它现在被认为是一种非阿片受体。 该基因的突变与幼年肌萎缩性侧索硬化症 16 有关。 …
SigmaR1 shapes rough endoplasmic reticulum membrane sheets
2024年10月7日 · High-resolution live cell imaging and electron tomography assign SigmaR1 as an ER sheet-localized factor whose levels determine the amount of rough ER sheets in cells.
SIGMAR1 sigma non-opioid intracellular receptor 1 [ (human)]
2025年1月4日 · SIGMAR1 is an alternative upstream STAT3 activator in addition to IL6/JAK signalling pathway. Combination of AAG8 antagonist and very low concentration of a MEK …
Sigma-1 receptor recruits LC3 mRNA to ER-associated ... - Cell Press
2024年8月27日 · SigmaR1 (S1R) is an RNA-binding ER membrane protein that recruits LC3B mRNA to the ER. S1R interacts with the 3′ UTR of LC3B mRNA to promote its translation. …
Sigmar1 sigma non-opioid intracellular receptor 1 [ (house …
2025年2月8日 · Sigma 1 receptor activation improves retinal structure and function in the Rho [P23H/+] mouse model of autosomal dominant retinitis pigmentosa. Specific detection and …
The molecular role of Sigmar1 in regulating mitochondrial …
2022年1月1日 · Sigmar1 is a widely expressed molecular chaperone protein in mammalian cell systems. Accumulating research demonstrated the cardioprotective roles of pharmacologic …
SIGMAR1/Sigma-1 receptor: a key regulator in stabilizing and ...
2024年10月10日 · Our study identified the endoplasmic reticulum (ER)-resident SIGMAR1 (sigma non-opioid intracellular receptor 1) as a critical regulator of the biosynthesis of Atg8-family …