2024年12月10日 · Get emergency medical help if you have signs of an allergic reaction to sildenafil: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking sildenafil and get emergency medical help if you have: heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;

2024年12月2日 · The 10 mg IV bolus dose is predicted to provide an equivalent pharmacological effect to that of 20 mg orally. Doses up to a maximum of 80 mg orally 3 times a day are supported by delayed clinical worsening with long-term use in clinical studies despite a lack of observed dose-response improvement in exercise ability in short-term clinical studies.

2025年2月18日 · Bioequivalence was established between the 20 mg tablet and the 10 mg/mL oral suspension when administered as a 20 mg single oral dose of sildenafil (as citrate). Metabolism and Excretion . Sildenafil is cleared predominantly by the CYP3A (major route) and cytochrome P450 2C9 (CYP2C9, minor route) hepatic microsomal isoenzymes.

It is not known if sildenafil is distributed into breast milk. 6. Response and effectiveness. Peak plasma concentrations of sildenafil are reached within 30 to 120 minutes of a single dose. Effects of sildenafil, when used for ED, are usually noticeable within 30 to 60 minutes of a single dose.

Erythromycin: Consider lower initial sildenafil dose (25 mg) Nitrates and nitrites (e.g., nitroglycerin, isosorbide dinitrate) Potentiation of vasodilatory effects (e.g., decrease in systolic BP of >25 mm Hg) of organic nitrates and nitrites; potentially life-threatening hypotension and/or hemodynamic compromise can result

2024年3月29日 · Grapefruit and grapefruit juice may interact with sildenafil and lead to unwanted side effects. Avoid the use of grapefruit products while taking sildenafil. Avoid using any other medicines to treat impotence, such as alprostadil or yohimbine, without first talking to your doctor. Viagra side effects

No tome sildenafil si usted también esta usando un nitrato para el dolor de pecho o problemas del corazón, incluyendo nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, y algunas de las drogas de diversión, como "poppers". Tomar sildenafil con un nitrato puede causar una disminución repentina y grave en la presión arterial.

2024年12月28日 · Adults—20 milligrams (mg) 3 times a day. Your doctor may adjust your dose as needed and tolerated. However, the dose is usually not more than 80 mg 3 times a day. Children 1 year of age and older weighing 45 kilograms (kg) or more—20 mg 3 times a day. Your doctor may adjust your dose as needed and tolerated.

2024年12月10日 · -Maximum dose: 20 mg orally three times a day Injection:-Initial dose: 2.5 or 10 mg IV bolus three times a day Comments:-No greater efficacy was achieved with oral doses higher than the maximum recommended dose.-A 10 mg injection dose is predicted to provide pharmacological effect equivalent to the 20 mg oral dose.

December 20, 2019; Viagra (sildenafil) "I'm a 29-year-old male. I have been using Viagra for a while to treat erectile dysfunction. I use the 50mg pills. I find Viagra to be extremely effective. The only side effect for me is a mild hot flush after taking one, which I …