SLC1A2 Gene - GeneCards | EAA2 Protein | EAA2 Antibody
2024年12月25日 · SLC1A2 (Solute Carrier Family 1 Member 2) is a Protein Coding gene. Diseases associated with SLC1A2 include Developmental And Epileptic Encephalopathy 41 …
清华大学药学院陈立功课题组应邀发表多篇综述文章阐述转运蛋白 …
谷氨酸转运蛋白 SLC1A1、SLC1A2 和 SLC1A3主要在大脑中表达，它们有助于防止谷氨酸兴奋性毒性，对多发性硬化症等中枢神经系统 (CNS) 疾病有重要的作用（图3）。 阳离子氨基酸转运 …
Excitatory amino acid transporter 2 - Wikipedia
Excitatory amino acid transporter 2 (EAAT2) also known as solute carrier family 1 member 2 (SLC1A2) and glutamate transporter 1 (GLT-1) is a protein that in humans is encoded by the …
溶质载体家族 1 成员 2（SLC1A2）基因 | MCE
膜结合蛋白是清除中枢神经系统突触细胞外空间的兴奋性神经递质谷氨酸的主要转运蛋白。 谷氨酸清除对于适当的突触激活和防止因谷氨酸受体过度激活造成的神经元损伤是必需的。 该基因 …
SLC1A2 solute carrier family 1 member 2 [ (human)]
SLC1A2 variant is associated with elevated anterior cingulate cortex glutamate and lifetime history of rapid cycling in mood disorders. The Na(+)/Ca(2+) exchanger (NCX) plays a dominant role …
The GLT-1 (EAAT2; slc1a2) glutamate transporter is essential for ...
Glutamate is the major excitatory neurotransmitter, and is inactivated by cellular uptake catalyzed mostly by the glutamate transporter subtypes GLT-1 (EAAT2) and GLAST (EAAT1). …
SLC1A2 - an overview | ScienceDirect Topics
The SLC1A2 gene is the principal membrane-bound transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous …
SLC1A2- 信号通路|蛋白抗体-华美生物
SLC1A2，即溶质载体家族1成员2，别名EAAT2、GLT-1等。 它是一种由SLC1A2基因编码的跨膜蛋白，主要在大脑神经元和胶质细胞中表达。 SLC1A2的作用机制涉及介导细胞外谷氨酸的转 …
SLC1A2 mediates refractory temporal lobe epilepsy with an initial ...
Tissue experiments suggested that Slc1a2 could genuinely ameliorate epilepsy through the glutamatergic synapse pathway, mitigate neuronal loss, and suppress astrocytosis and …
溶质载体家族 1 成员 2（Slc1a2）基因 | MCE
该基因编码的蛋白可启动高亲和力谷氨酸跨膜转运蛋白活性。 参与 L-谷氨酸跨膜转运。 位于几种细胞成分中，包括星形胶质细胞投射；树突;和突触前膜。 是质膜的组成部分。 膜蛋白复合物 …