SLC1A2 Gene - GeneCards | EAA2 Protein | EAA2 Antibody
Mar 30, 2025 · SLC1A2 (Solute Carrier Family 1 Member 2) is a Protein Coding gene. Diseases associated with SLC1A2 include Developmental And Epileptic Encephalopathy 41 and Non …
Excitatory amino acid transporter 2 - Wikipedia
Excitatory amino acid transporter 2 (EAAT2) also known as solute carrier family 1 member 2 (SLC1A2) and glutamate transporter 1 (GLT-1) is a protein that in humans is encoded by the …
The severity of SLC1A2-associated neurodevelopmental ...
The observed associations between functional effects and clinical phenotypes produced by these variants offer valuable insights for future predictions of progression and severity of SLC1A2 …
SLC1A2 solute carrier family 1 member 2 [ (human)]
SLC1A2 variant is associated with elevated anterior cingulate cortex glutamate and lifetime history of rapid cycling in mood disorders. The Na(+)/Ca(2+) exchanger (NCX) plays a dominant role …
Recurrent SLC1A2 variants cause epilepsy via a dominant ...
SLC1A2 is a trimeric transporter essential for clearing glutamate from neuronal synapses. Recurrent de novo SLC1A2 missense variants cause a severe, early onset developmental and …
Functional investigation of SLC1A2 variants associated with ...
Dec 21, 2022 · Astrocytic glutamate transporter GLT-1 is responsible for preventing excitotoxicity via clearing extracellular accumulated glutamate. Previously, three variants (G82R, L85P, and …
Slc1a2 solute carrier family 1 (glial high affinity glutamate ...
Feb 8, 2025 · Enables cysteine transmembrane transporter activity; high-affinity L-glutamate transmembrane transporter activity; and monoatomic anion transmembrane transporter …