SLC38A9 Gene - GeneCards | S38A9 Protein | S38A9 Antibody
2024年12月25日 · SLC38A9 (Solute Carrier Family 38 Member 9) is a Protein Coding gene. Diseases associated with SLC38A9 include Lung Cancer and Epilepsy . Among its related …
【Science新发现】溶酶体胆固醇通过SLC38A9-NPC1信号复合体激 …
2018年2月1日 · 今日，Science刊登了一篇名为 “Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex”的文章。来自加州大学伯克利分校的研究者发 …
溶质载体家族 38 成员 9（SLC38A9）基因 | MCE
启用 L-精氨酸跨膜转运蛋白活性和 L-亮氨酸跨膜转运蛋白活性。 参与氨基酸跨膜转运；细胞对氨基酸刺激的反应；和 TOR 信号的正向调节。 位于晚期内体和溶酶体膜。 是溶酶体膜的组成 …
mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino …
2017年10月19日 · Activation of mTORC1 by arginine requires SLC38A9, a poorly understood lysosomal membrane protein with homology to amino acid transporters. Here, we validate that …
SLC38A9 is a component of the lysosomal amino acid sensing
2015年1月7日 · Here we describe the uncharacterized human member 9 of the solute carrier family 38 (SLC38A9) as a lysosomal membrane-resident protein competent in amino acid …
Lysosomal cholesterol activates mTORC1 via an SLC38A9
2017年3月24日 · The lysosomal transmembrane protein, SLC38A9, is required for mTORC1 activation by cholesterol through conserved cholesterol-responsive motifs. Moreover, …
SLC38A9 is a component of the lysosomal amino acid sensing ... - PubMed
2015年3月26日 · Here we describe the uncharacterized human member 9 of the solute carrier family 38 (SLC38A9) as a lysosomal membrane-resident protein competent in amino acid …
Cell：溶酶体释放必需氨基酸以及蛋白质作为营养物质时激活mTORC1的SLC38A9 …
在此项研究中，研究者证实SLC38A9是mTORC1途径的精氨酸传感器，并且发现SLC38A9在调节氨基酸平衡中有意想不到的中心作用。 SLC38A9以精氨酸调节的方式介导溶酶体中许多必需 …
Lysosomal amino acid transporter SLC38A9 signals arginine ... - Science
2015年1月7日 · Here, we identify SLC38A9, an uncharacterized protein with sequence similarity to amino acid transporters, as a lysosomal transmembrane protein that interacts with the Rag …
SLC38A9 solute carrier family 38 member 9 [ (human)]
2025年1月5日 · SLC38A9 is a physical and functional component of the amino acid sensing machinery that controls the activation of mTOR; SLC38A9 functions upstream of the Rag …