2015年7月15日 · In the present study, we show that the E3 SUMO (small ubiquitin-related modifier) ligase AtSIZ1 regulates gibberellic acid signalling in Arabidopsis species by sumoylating SLY1.

2020年1月10日 · Arabidopsis SIZ1 encodes a SUMO E3 ligase to regulate abiotic and biotic stress responses. Among SIZ1 or mammalian PIAS orthologs, plant SIZ1 proteins contain the plant homeodomain (PHD)...

2016年4月29日 · Here we show that SUMO (small ubiquitin-like modifier) modification enhances COP1 activity. Loss-of-function siz1 mutant seedlings exhibit a weak constitutive photomorphogenic phenotype. SIZ1 physically interacts with …

2010年11月16日 · However, the biological function of the SUMO E3 ligase, SIZ1, in rice (Oryza sativa) is still under investigation. In this study, we employed two different genetic approaches, the use of siz1 T-DNA mutant and SIZ1 -RNAi transgenic plants, to …

在本研究中，我们显示E3 SUMO（小的泛素相关修饰剂）连接酶AtSIZ1通过将SLY1合成来调节拟南芥物种中的赤霉素信号。与野生型植物相比，siz1-2突变体中SLY1的丰富程度较低，但是ga1-3（RGA）的DELLA蛋白阻遏物在siz1-2突变体中比在野生型植物中更丰富。

2015年7月6日 · In the present study, we show that the E3 SUMO (small ubiquitin-related modifier) ligase AtSIZ1 regulates gibberellic acid signalling in Arabidopsis species by sumoylating SLY1.

In transgenic plants, suppression of AtSIZ1 caused rapid post-translational decay of SLEEPY1 (SLY1), a positive regulator of GA signaling, during germination, and inducible AtSIZ1 overexpression led to increased SLY1 levels.

这一篇是2016年中科院植物所金京波研究组发表在《PLOS Genetics》上的"An Arabidopsis SUMO E3 Ligase, SIZ1, Negatively Regulates Photomorphogenesis by Promoting COP1 Activity"，该课题组主要以 拟南芥 和大豆为研究体系，鉴定SUMO化及组蛋白去甲基化调控植物发育、激素及环境胁迫的表观 ...

2021年10月3日 · In siz1, the expression of ALMT1 is enhanced and the removal of Fe from Pi-deficient medium suppressed the siz1 mutant phenotype. In this report, we show that siz1 overaccumulates Fe in its root apoplasts, and consequently, produces more hydroxyl radicals, which are detrimental to root growth.

2020年3月1日 · SIZ1 regulates anthocyanin accumulation via sumoylation of MYB75. SIZ1 increases MYB75 stability under high light conditions in Arabidopsis. Sumoylation is one of post-translational modification (PTM) in which SUMO (small ubiquitin-like modifier) are covalently conjugated to protein substrates through a range of biochemical steps.