Diablo homolog - Wikipedia
Diablo homolog (DIABLO) is a mitochondrial protein that in humans is encoded by the DIABLO (direct IAP binding protein with low pI) gene on chromosome 12. [5] [6] [7] DIABLO is also …
Role of Smac/DIABLO in cancer progression - PMC - PubMed …
Second mitochondria-derived activator of caspase/direct inhibitor of apoptosis-binding protein with low pI (Smac/DIABLO) is a proapoptogenic mitochondrial protein that is released to the cytosol …
线粒体蛋白Smac/DIABLO与细胞凋亡 - 百度学术
第二个线粒体衍生的半胱氨酸蛋白酶激活剂 (Smac/DIABLO)是近年来新发现的一种线粒体蛋白, 在正常细胞内Smac定位于线粒体.受到凋亡刺激时, Smac蛋白的线粒体定位信号肽被切除, 能够 …
SMAC/Diablo controls proliferation of cancer cells by ... - PubMed
SMAC/Diablo, a pro-apoptotic protein, yet it is overexpressed in several cancer types. We have described a noncanonical function for SMAC/Diablo as a regulator of lipid synthesis during …
A New Role for the Mitochondrial Pro-apoptotic Protein SMAC/Diablo …
2018年3月7日 · We demonstrate that SMAC/Diablo possesses non-apoptotic functions associated with the regulation of phospholipid (PL) biosynthetic pathways essential for cancer …
Smac /DIABLO 与肿瘤治疗 - zlfzyj.com
Smac／DIABLO被称为第二个线粒体来源的胱氨酸酶激活剂（second mitochondria-derived activator of caspase，Smac）或低等电点IAP直接结合蛋白（direct IAP-binding protein with …
Smac / DIABLO促进胱天蛋白酶促进活性的分子决定因素及其在死 …
Smac / DIABLO是一种线粒体蛋白，在凋亡过程中与细胞色素c一起释放，并通过中和凋亡蛋白（IAP）抑制剂促进细胞色素c依赖性胱天蛋白酶的活化。 我们提供的证据表明，Smac / …
Role of Smac/DIABLO in cancer progression - PubMed
2008年9月26日 · Second mitochondria-derived activator of caspase/direct inhibitor of apoptosis-binding protein with low pI (Smac/DIABLO) is a proapoptogenic mitochondrial protein that is …
Structural basis of IAP recognition by Smac/DIABLO - Nature
2000年12月21日 · Our results show that the N-terminal four residues (Ala-Val-Pro-Ile) in Smac/DIABLO recognize a surface groove on BIR3, with the first residue Ala binding a …
线粒体促凋亡蛋白Smac_DIABLO及其与肿瘤的关系 - 百度文库
[ 摘要 ] Sm ac /D I ABLO 即第 2个线粒体衍生的半胱天冬蛋白酶 激活剂 /低 pI的 IAP 直接 结合蛋 白, 是近年发 现的一 种线粒 体促凋亡蛋白, 存在于线粒体并通过拮抗凋亡抑制 蛋白 ( IAP s) 的 …