SMAD (protein) - Wikipedia
Smads (or SMADs) comprise a family of structurally similar proteins that are the main signal transducers for receptors of the transforming growth factor beta (TGF-B) superfamily, which …
Mothers against decapentaplegic homolog 2 - Wikipedia
Mothers against decapentaplegic homolog 2, also known as SMAD family member 2 or SMAD2, is a protein that in humans is encoded by the SMAD2 gene. [5] [6] MAD homolog 2 belongs to …
TGF-β信号通路与Smad家族蛋白 - 纽普生物
Smad蛋白（Smad是由线虫的Sma和果蝇的Mad缩写而来） 是TGF-β家族受体下游的信号转导分子[1,2]。在哺乳动物中有八个Smad蛋白, Smad1、 Smad1、 ...、 Smad8。 根据在TGF-β信号 …
SMAD2 Gene - GeneCards | SMAD2 Protein | SMAD2 Antibody
2024年12月25日 · SMAD2 (SMAD Family Member 2) is a Protein Coding gene. Diseases associated with SMAD2 include Loeys-Dietz Syndrome 6 and Congenital Heart Defects, …
易基因：上海交大王琼团队揭示TGFβ-Smad信号通路和DNA甲基化 …
2024年12月3日 · 本研究通过RNA-seq、ChIP-seq、CUT&Tag、ATAC-seq、WGBS等分析揭示了Smad2/3在mESCs向EpiLCs转变过程中通过诱导Dnmt3b表达来调控DNA甲基化模式，从而 …
Smad2 and Smad3 have differential sensitivity in relaying TGFβ ...
2016年2月24日 · Here, we show that Smad3 is an insensitive TGFβ transducer as compared with Smad2. Smad3 preferentially localizes within the nucleus and is thus sequestered from …
The SMAD2/3 interactome reveals that TGFβ controls m 6 A mRNA ... - Nature
2018年2月28日 · The SMAD2 and SMAD3 protein interactome links TGFβ signalling to diverse effectors including m6A methyltransferase, which has a role in regulating differentiation of …
SMAD2 SMAD family member 2 [ Homo sapiens (human) ]
2025年3月4日 · SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming …
Smad2 linker region phosphorylation is an autonomous cell …
2020年4月1日 · The R-Smads, Smad2 and Smad3 have distinct roles in cell biology. Smad2 and 3 are activated by TGF-β and activin receptors, TβRI and ActRIIB, through phosphorylation of …
SMAD2和SMAD3在人胚胎干细胞分化过程中的不同调控作用
在SMAD2KO和SMAD3KO细胞中分别过表达SMAD2和SMAD3质粒，通过Western blotting检测SMAD2和SMAD3蛋白回补的效果，并利用实时定量PCR（real-time quantitative reverse …