
SMAD4 Gene - GeneCards | SMAD4 Protein | SMAD4 Antibody
2024年12月25日 · SMAD4 (SMAD Family Member 4) is a Protein Coding gene. Diseases associated with SMAD4 include Myhre Syndrome and Juvenile Polyposis Syndrome. Among …
Mothers against decapentaplegic homolog 4 - Wikipedia
SMAD4, also called SMAD family member 4, Mothers against decapentaplegic homolog 4, or DPC4 (Deleted in Pancreatic Cancer-4) is a highly conserved protein present in all metazoans. …
SMAD4 gene - MedlinePlus
The SMAD4 gene provides instructions for making a protein involved in transmitting chemical signals from the cell surface to the nucleus. The SMAD4 protein is part of a signaling pathway, …
Pathology Outlines - SMAD4 / DPC4
2021年6月18日 · SMAD4 immunohistochemistry shows loss of nuclear expression in tumor cells, confirming the diagnosis. A patient presents with hernia sac mass, resection of which showed …
The multifaceted role of SMAD4 in immune cell function
2025年3月1日 · Understanding SMAD4's role in immune cells is crucial, as its dysregulation can lead to autoimmune disorders, chronic inflammation, and immune deficiencies. The review …
Smad4 / DPC4 - PubMed
Smad4 or DPC4 belongs to a family of signal transduction proteins that are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to transforming …
SMAD4 feedback regulates the canonical TGF-β signaling
2018年2月2日 · Here we provide evidence that SMAD4, a core component of the canonical TGF-β signaling pathway, regulates the canonical TGF-β signaling pathway in porcine granulosa …
The Secret Life of Smad4 - Cell Press
2009年1月9日 · Smad4 is an important mediator of signaling by TGFβ family members that is presumed to be controlled by the phosphorylation status of its partners, the receptor-regulated …
Entry - *600993 - SMAD FAMILY MEMBER 4; SMAD4 - OMIM
The SMAD4 gene encodes a protein involved in signal transduction of the transforming growth factor-beta (see, e.g., TGFB1, 190180) superfamily and bone morphogenic proteins (see, e.g., …
SMAD4 SMAD family member 4 [ Homo sapiens (human) ]
2025年2月20日 · Title: SMAD4 mutations causing Myhre syndrome are under positive selection in the male germline. Investigating the impact of SMAD2 and SMAD4 downregulation in …
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