
SMAD5 Gene - GeneCards | SMAD5 Protein | SMAD5 Antibody
2024年12月25日 · SMAD5 (SMAD Family Member 5) is a Protein Coding gene. Diseases associated with SMAD5 include Fibrodysplasia Ossificans Progressiva and Pulpitis. Among its related pathways are TGF-beta receptor signaling in skeletal dysplasias and TGF-Beta Pathway.
Exploring Smad5: a review to pave the way for a deeper …
2024年11月22日 · Smad5 (small mothers against decapentaplegic 5) protein is a receptor-regulated member of the Smad family proteins, mainly participating in the bone morphogenetic protein (BMP) signaling pathway in its phosphorylated form.
SMAD5 signaling: more than meets the nuclei | Cell Research
2017年8月15日 · A recent study by Fang et al. in Cell Research adds to this biological complexity by demonstrating an atypical cytoplasmic role for SMAD5 in modulating the bioenergetic homeostasis (i.e.,...
Smad5 acts as an intracellular pH messenger and maintains
2017年7月4日 · Together, our findings indicate that Smad5 acts as a pHi messenger and maintains the bioenergetic homeostasis of cells by regulating cytoplasmic metabolic machinery. Given that most biological...
Smad 家族 (Smad Family) | 重组蛋白 | MCE - MCE-生物活性分子 ...
SMAD5 (dwarfin C, JV5-1, MAD5) 是一种受体激活的 Smad (R-Smad),属于 dwarfin/SMAD 家族。SMAD5 蛋白受到 I 型 TGF-β 受体激活,而与 SMAD4 结合形成三聚体活性形式。SMAD5 参与 BMP 信号通路,调控成骨过程,与胚胎发育有关。
Exploring Smad5: a review to pave the way for a deeper ... - PubMed
2024年11月22日 · Smad5 (small mothers against decapentaplegic 5) protein is a receptor-regulated member of the Smad family proteins, mainly participating in the bone morphogenetic protein (BMP) signaling pathway in its phosphorylated form. This article will provide a detailed review of Smad5, focusing on its gene ch …
SMAD5 SMAD family member 5 [ (human)] - National Center for ...
We identified SMAD5 as direct target of miR-145, the suppressed expression of which consequently led to increased cell proliferation and migration/invasion. Smad5 acts as a intracellular pH messenger and maintains the bioenergetic homeostasis of cells by regulating cytoplasmic metabolic machinery.
Smad5: signaling roles in hematopoiesis and osteogenesis
2004年5月1日 · Smad5 belongs to the receptor-activated Smad that function as intracellular signal transducers for transforming growth factor-β superfamily. Smad5 protein is composed of N-terminal domain responsible for DNA-binding, C-terminal domain primarily required for protein-protein interactions, and the linker region containing motif essential for ...
SMAD5 | 重组蛋白 - MCE
SMAD5 是一种受体激活的 Smad (R-Smad),也称为 dwarfin C, JV5-1 和 MAD5,属于 dwarfin/SMAD 家族。 SMAD5 蛋白由负责 DNA 结合的 N端结构域、主要用于蛋白质-蛋白质相互作用的 C 端结构域和包含泛素化降解所必需的基序的连接区组成。
Smad5 SMAD family member 5 [ (house mouse)] - National …
2025年2月8日 · Smad5 determines murine amnion fate through the control of bone morphogenetic protein expression and signalling levels; Association of runx2 with smad 5 is essential for osteogenic induction of C2C12 cells; overexpression of Smurf1 specifically promotes Smad1 and Smad5 ubiquitination and degradation in embryonic lung epithelium