
什么是小核糖核酸(sRNA,small RNA),在学术界现在对sRNA …
small RNA是指包括 micro RNA (miRNA)、small interference RNA (siRNA)、piwi-interacting RNA (piRNA)在内的一类通常长度在200nt以下的非编码RNA分子。 有,可以去查朱玉贤的 《现代分子生物学》 和沃森的《基因的分子生物学》第七版,我考研的时候记过现在不记得了哈哈. 知乎,中文互联网高质量的问答社区和创作者聚集的原创内容平台,于 2011 年 1 月正式上线,以「让人们更好的分享知识、经验和见解,找到自己的解答」为品牌使命。
Small size, big impact: how studies of small DNA tumour viruses ...
Intense study of three families of small tumour viruses with double-stranded DNA genomes, carried out over 50 years, has had a profound impact on biology. The polyomaviruses and papillomaviruses have circular DNA genomes of approximately 5000 and approximately 8000 base-pairs, respectively, and thus encode only a handful of proteins.
Small DNA Viruses - ScienceDirect
1971年1月1日 · The detailed classification of the small deoxyribonucleic acid (DNA) viruses has as yet not been finalized; however, the generic name, that is, parvovirus has been approved by the Executive Committee of the International Committee on Nomenclature of Viruses, while the name, picodnavirus has not.
Small extrachromosomal circular DNAs, microDNA, produce short ...
2019年5月5日 · We have tested functional capabilities of microDNA by creating artificial microDNA molecules mimicking known microDNA sequences and have discovered that they express functional small regulatory RNA including microRNA and novel si-like RNA. MicroDNA are transcribed in vitro and in vivo independent of a canonical promoter sequence.
A Mechanism of Gene Amplification Driven by Small DNA …
Here we demonstrate that small DNAs can amplify a chromosomal region, generating either tandem duplications or acentric extrachromosomal DNA circles. Small fragment-driven DNA amplification (SFDA) occurs with a frequency that increases with the length of homology between the small DNAs and the target chromosomal regions.
Molecular self-assembly of stable and small branched DNA …
2024年12月1日 · In the present communication, we report smaller and stable branched DNA (bDNA) which is of critical significance for biomedical applications. In this study, a novel strategy has been used in identifying stable bDNA nanostructures with a minimum number of Watson-Crick base pairings.
Rapid Multiplex Small DNA Sequencing on the MinION Nanopore …
In this study, an ultra-rapid multiplex library preparation and sequencing method for the MinION is presented and applied to accurately test normal diploid and aneuploidy samples’ genomic DNA in under three hours, including library preparation and sequencing.
Small genes, big implications - Scienceline
2019年12月21日 · Small genes are chains of 50 or fewer nucleotides — the molecules that make up DNA. These genes contain instructions for making small proteins and are more difficult to recognize and generally considered less important than larger genes, which are thought to hold most inherited genetic information.
2024年9月13日 · We selected four heterologous sequences that show insulator activity in plants (λ -EXOB, BEAD-1C, UASrpg, and a Drosophila gypsy element, refs. 12,17,18,25), and two synthetic sequences (sIns1 and sIns2) for which preliminary …
Smallest genome clocks in at 182 genes : Nature News
2006年10月12日 · Researchers now say that a symbiotic bacterium called Carsonella ruddii, which lives off sap-feeding insects, has taken the record for smallest genome with just 159,662 'letters' (or base pairs) of...