Size matters: HDL particle populations and the risk of infection
2023年2月15日 · Small HDLs are potent promoters of macrophage cholesterol efflux by ATP-binding cassette transporter A1 (ABCA1), the first key step in cholesterol export 7, whereas …
HDL particle number and size as predictors of cardiovascular …
Particle Numbers of Large vs. Small HDL. HDL particles are highly heterogeneous in structure, composition, metabolism, and function. Distinct HDL subpopulations might, therefore, exert …
Low levels of small HDL particles predict but do not influence risk …
2023年10月9日 · Low number of small HDL particles are associated with increased hazard of sepsis, sepsis-related death, and sepsis-related critical care admission. However, genetic …
Cardiovasc Res：低水平的小HDL颗粒与传染性疾病发病率和死亡 …
2022年12月25日 · 核磁共振(nmr)波谱允许测量hdl颗粒计数，并允许根据颗粒大小进行分类。 近日，心 血管 领域权威杂志Cardiovasc Res上发表了一篇研究文章，研究人员旨在评估较低的不 …
Lower levels of small HDL particles associated with increased ...
2023年5月2日 · In multifactorial adjusted analyses, low number of small and medium HDL particles was associated with increased risk of any infection and infectious disease-related …
HDL Particle Size and Functional Heterogeneity
2016年9月2日 · Lipid-poor and small HDL displayed both high capacity for ABCA1-mediated cholesterol efflux and strong anti-inflammatory action, whereas the larger particles showed …
Small HDL Promotes Cholesterol Efflux by the ABCA1 Pathway in ...
2015年3月27日 · In this issue, Du et al 10 challenge this notion by providing strong evidence that small, dense HDL particles are potent acceptors of cholesterol exported from macrophages by …
Small, Dense High-Density Lipoprotein-3 Particles Are Enriched in ...
2013年10月3日 · HDL subpopulations can be distinct in their biological function; small, dense HDL3, which are enriched in bioactive lipids and proteins 8, 14 and display distinct structure, …
Lower levels of small HDL particles associated with increased ...
2022年12月20日 · Low levels of HDL cholesterol have been associated with increased risk of infectious disease morbidity and mortality. Nuclear magnetic resonance (NMR) spectroscopy …
Association of Small HDL Subclasses with Mortality Risk in ... - MDPI
2024年12月11日 · High-density lipoproteins (HDL) exist in various subclasses, with smaller HDL particles possessing the highest anti-oxidative and anti-inflammatory properties. …