2024年2月12日 · Due to its ability to buffer pH and influence acid-base shifts, sodium bicarbonate can also affect many drug-drug interactions, including fluoroquinolones such as levofloxacin and tetracyclines such as doxycycline and minocycline.

Sodium bicarbonate is a compound used for the symptomatic treatment of heartburn, acid indigestion, and upset stomach as well as the treatment of metabolic acidosis associated with conditions such as severe renal disease and circulatory insufficiency due to shock.

In this article, we review the data regarding the impact of systemic sodium bicarbonate administration in the management of certain poisonings including sodium channel blocker toxicities, salicylate overdose, and ingestion of some toxic alcohols and in various pharmacological toxicities.

2024年12月21日 · Herein, we discuss the effects of sodium bicarbonate on overall mortality, CSF pH, neurological status, cerebral edema, and oxygen delivery. We also highlight the potential pathophysiology of sodium bicarbonate-induced neurological dysfunction.

2024年2月12日 · Sodium bicarbonate is a multifaceted medication that plays a crucial role in managing and treating diverse disease pathologies. This activity delves into the expansive applications of sodium bicarbonate, providing healthcare professionals with a nuanced understanding of its indications, mechanism of …

Sodium bicarbonate is indicated in the treatment of metabolic acidosis which may occur in severe renal disease. Learn about side effects, dosages, drug interactions, and more.

The second study, a multicenter randomized controlled trial (Sodium Bicarbonate Therapy for Patients with Severe Metabolic Acidaemia in the Intensive Care Unit), 27 in 400 critically ill patients with severe acidemia (pH less than 7.2; Pa co 2, 45 mmHg; lactate greater than 2 mM), found that early bicarbonate infusion, with a target pH of 7.30 ...

2024年3月17日 · This article provides an in-depth review of sodium bicarbonate's pharmacological properties, clinical indications, mechanisms of action, administration protocols, and dosage considerations. It...