2025年1月8日 · Sotalol hydrochloride tablets, USP (AF) are an antiarrhythmic drug with Class II (beta-adrenoreceptor blocking) and Class III (cardiac action potential duration prolongation) properties. It is supplied as a white, capsule-shaped tablet for oral administration. Sotalol hydrochloride is a white, crystalline solid with a molecular weight of 308.8.

2016年6月18日 · Sotalol is available as the trade name Betapace and Betapace AF. These two trade names have different indications and one product should never be substituted for the other product because of significant differences in labeling (i.e., indications, dosing administration, safety information, and patient package insert information).

2025年1月20日 · Sotalol can cause life threatening ventricular tachycardia associated with QT interval prolongation. Do not initiate sotalol therapy if the baseline QTc is longer than 450 ms. If the QT interval prolongs to 500 ms or greater, the dose must be reduced, the interval between doses prolonged, or the drug discontinued.

2023年10月18日 · Sotalol was first FDA-approved on October 30, 1992. Warnings. You should not use sotalol if you have asthma, low potassium, or a serious heart condition such as severe heart failure, long QT syndrome, slow heartbeats that have caused you to faint, "sick sinus syndrome" or "AV block" (unless you have a pacemaker).

Sotalol Pregnancy and Breastfeeding Warnings. Brand names: Betapace, Betapace AF, Sorine, Sotalol Hydrochloride AF, Sotylize. Pregnancy Warnings; Breastfeeding Warnings; Sotalol Pregnancy Warnings. Benefit should outweigh risk. AU TGA pregnancy category: C US FDA pregnancy category: B Comments:

More about Sotalol Ratings & Reviews Metoprolol has an average rating of 5.8 out of 10 from a total of 651 ratings on Drugs.com. 41% of reviewers reported a positive effect, while 33% reported a negative effect.

2024年1月31日 · SORINE (sotalol hydrochloride, USP) is supplied as a white, capsule-shaped tablet for oral administration. Sotalol hydrochloride, USP is a white, crystalline solid with a molecular weight of 308.8. It is hydrophilic, soluble in water, propylene glycol and ethanol, but is only slightly soluble in chloroform.

2024年1月24日 · Hospitalize patients being initiated or re-initiated on sotalol for at least 3 days or until steady-state drug levels are achieved in a facility that can provide cardiac resuscitation and continuous electrocardiographic monitoring. Initiate oral sotalol therapy in the presence of personnel trained in the management of serious arrhythmias.

2024年4月10日 · Based on experience with oral sotalol hydrochloride, the usual therapeutic effect should be observed with IV dosages of 75–150 mg once or twice daily; however, patients with life-threatening refractory ventricular arrhythmias have received higher dosages (e.g., oral dosages of 240–320 mg once or twice daily corresponding to IV dosages of ...

Sotalol Interactions. There are 621 drugs known to interact with sotalol, along with 20 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 233 are major, 358 are moderate, and 30 are minor.