2024年12月25日 · SOX3 (SRY-Box Transcription Factor 3) is a Protein Coding gene. Diseases associated with SOX3 include Intellectual Developmental Disorder, X-Linked, With …

SRY-box transcription factor 3, SOX3, is a transcription factor that is encoded by the SOX3 gene. This gene is responsible for ensuring proper embryonic development and determining the fate …

2020年4月21日 · Using a panel of spermatogonial cell marker genes, we demonstrate that Sox3 is expressed within the committed progenitor fraction of the undifferentiated spermatogonial …

Results show that SOX3 is upregulated in human osteosarcoma (OS) tissues and provide evidence that SOX3 promotes migration, invasiveness, and EMT in OS cells via transcriptional …

SOX3 is a protein that belongs to the B group of the large Sox proteins. It is involved in neural ectoderm specification and acts as a mesodermal suppressor in the ectoderm by negatively …

该基因编码参与胚胎发育调控和细胞命运决定的转录因子 SOX (SRY 相关 HMG 盒) 家族成员。 编码的蛋白质在与其他蛋白质形成蛋白质复合物后可以充当转录调节剂。 该基因的突变与伴有 …

Isolation and sequencing of the gene showed 97.2% similarity to the protein encoded by the mouse Sox3 gene which is also located on the X chromosome. The RACE (rapid amplification …

Some SOX TFs suspend neural progenitors in proliferative, stem-like state and prevent their differentiation. SOX proteins function as pioneer factors that occupy silenced target genes and …

2023年12月25日 · Go to Variation Viewer for SOX3 variants Summary This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the …

First, most Sox factors are expressed in multiple types of stem/progenitor cell types or tissues. Second, many Sox factors act redundantly in the maintenance of stem cells (e.g., Sox1, Sox2, …