2024年12月25日 · SPATA16 (Spermatogenesis Associated 16) is a Protein Coding gene. Diseases associated with SPATA16 include Spermatogenic Failure 6 and Male Infertility Due …

SPATA16, also known as NYD-SP12, is a developmental protein that aids in differentiation of germ cells for spermatogenesis and participates in acrosome formation for appropriate sperm …

该基因编码属于四肽重复样超家族的睾丸特异性蛋白质。 编码的蛋白质定位于高尔基体，并可能在精子发生中发挥作用。 [RefSeq 提供，2010 年 5 月] This gene encodes a testis-specific …

2017年10月21日 · Globozoospermic patients carried a homozygous point mutation in SPATA16 at 848G→A/R283Q. We generated CRISPR/Cas9-mediated mutant mice with the same amino …

Study showed that SPATA16 defects could be associated with an abnormal meiosis leading to a particular morphological sperm defect of double/multiple round-headed and multi-flagella and …

2021年10月17日 · A recent genetic analysis of infertile globozoospermic patients identified causative mutations in three genes: a protein interacting with C kinase 1 (PICK1), dpy 19-like …

2025年2月8日 · This study demonstrates that Spata16 is indispensable for male fertility in mice, as well as in humans. Mutation of SPATA16 is associated with globozoospermia. Case …

在本项目中，我们通过制备特异性的spata16抗体，研究了spata16在小鼠组织中的特异表达，结果发现spata16为睾丸特异性表达，其表达量随着精子发生的过程逐步增加，在出生后6周达到最 …

Globozoospermic patients carried a homozygous point mutation in SPATA16 at 848G→A/R283Q. We generated CRISPR/Cas9-mediated mutant mice with the same amino acid substitution in …

Spermatogenesis associated 16 (SPATA16) gene plays an important role in acrosome formation. In this study, we analysed SPATA16 promoter methylation in 29 oligozoospermic infertile and …