Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane in eukaryotic cells. Spectrin forms pentagonal or hexagonal arrangements, forming a scaffold …

Introduction Spectrin is an abundant protein in the nervous system, comprising 2.4% of total protein in mammalian brain homogenates. Spectrin is an unusually large protein with a native …

Spectrin is a large, cytoskeletal, and heterodimeric protein composed of modular structure of α and β subunits, it typically contains 106 contiguous amino acid sequence motifs called …

2021年5月24日 · Its name derives from the French and Latin words for ghost and apparition (spectre and spectrum, respectively), since it was originally isolated from the membranes of …

There is evidence of spectrin’s contribution to the processes of morphogenesis which are connected to its interactions with adhesion molecules, membrane proteins (and perhaps …

2013年12月5日 · Spectrin is a large, cytoskeletal, and heterodimeric protein composed of modular structure of α and β subunits, it typically contains 106 contiguous amino acid sequence motifs …

2014年2月1日 · A major component of this network is spectrin, which in erythrocytes is a tetrameric or higher oligomeric protein composed of antiparallel filamentous heterodimers, of α …

This review discusses the spectrin superfamily of proteins that function to connect cytoskeletal elements to each other, the cell membrane, and the nucleus. The signature domain is the …

2023年1月25日 · Spectrins bind ankyrins, which in turn stabilize membrane-spanning proteins such as cell adhesion molecules and ion channels. b, Spectrin tetramers assemble by linking …

The role of spectrin in endocytosis still remains poorly understood. Here, I summarize current knowledge of spectrin function, spectrin-based cytoskeleton and endocytosis of erythrocytes, …