Spidroins are the main proteins in spider silk. Different types of spider silk contain different spidroins, all of which are members of a single protein family. [1] . The most-researched type of spidroins are the major ampullate silk proteins (MaSp) used in the construction of dragline silk, the strongest type of spider silk.

2022年12月1日 · Spiders impress us with their sophisticated use of silk and the stunningly distinct silk proteins (spidroins) in each spider species. Understanding how silks and spidroins function and evolve within the spider world is one profound interest to …

2022年10月12日 · Spider silk is a prime example of an extended phenotype, whose extraordinary mechanical properties are governed by the underlying composition and structure of protein building blocks called spidroins. All spiders use silk for various critical purposes, including foraging, locomotion, nesting, mating, egg protection, and communication (1).

2010年8月9日 · Spidroins are a unique family of large, structural proteins that make up the bulk of spider silk fibers. Due to the highly variable nature of their repetitive sequences, spidroin evolutionary relationships have principally been determined from their non-repetitive carboxy (C)-terminal domains, though they offer limited character data.

2022年8月15日 · Here, we report that recombinant miniature spidroins, and importantly also the N-terminal domain (NT) on its own, rapidly form self-supporting and transparent hydrogels at 37 °C.

2017年5月1日 · Spider silks are largely composed of spidroins, a unique family of structural proteins. To investigate spidroin genes systematically, we constructed the first genome of an orb-weaving spider: the...

2024年5月31日 · Here the authors investigate the structure of the fibers formed by a C-terminal domain of a major spidroin: the study elucidates the mechanisms by which spidroins are transformed from soluble...

2024年2月6日 · Two types of spidroin-derived modular proteins have been designed and the fabricated fibers demonstrate a toughness of up to 200 MJ/m 3, achieving the highest value among the reported artificial spider silks.

2024年3月23日 · In this paper, a biomimetic spidroin sequence design with high yield and good spinning performance is reported, and a strategy for electrospinning to produce an artificial nanogenerator is explored. Among the natural macroscopic materials, the ampulla dragline is one of the main materials with excellent biocompatibility and mechanical properties.

2024年10月22日 · Using these novel genomes along with 25 previously published ones, we examine the evolutionary history of spidroin gene and structural hox cluster diversity. Our assemblies provide critical genomic resources to facilitate …