SQRRR or SQ3R is a reading comprehension method named for its five steps: survey, question, read, recite, and review. The method was introduced by Francis P. Robinson in his 1941 book Effective Study. [1] The method offers a less passive approach to reading textbook material. Similar methods include PQRST and KWL table. [2]

2017年2月14日 · In this study, we have identified a sulfide-responsive transcriptional repressor, SqrR, that functions as a master regulator of sulfide-dependent gene expression in the purple photosynthetic bacterium Rhodobacter capsulatus. SqrR has three cysteine residues, two of which, C41 and C107, are conserved in SqrR homologs from other bacteria.

2022年4月26日 · We found that the persulfide-responsive transcription factor SqrR may repress the expression of several GTA-related genes in the photosynthetic bacterium Rhodobacter capsulatus. Here, we show that the sqrR deletion mutant (Δ sqrR) produces higher amounts of intra- and extracellular GTA and gene transfer activity than the wild type (WT).

2017年2月28日 · These results establish that SqrR is a sensor of H 2 S-derived reactive sulfur species that maintain sulfide homeostasis in this photosynthetic bacterium and reveal the mechanism of sulfide-dependent transcriptional derepression …

In this study, we have identified a sulfide-responsive transcriptional repres- sor, SqrR, that functions as a maste r regulator of sulfide-dependent gene expression in the purple photosynthetic bacterium Rhodobacter capsulatus. SqrR has three cysteine residues, two of which, C41 and C107, are conserved in SqrR homologs from other bacteria.

2023年2月10日 · The oxidation of SqrR was confirmed by a mass spectrometry-based kinetic profiling strategy that showed distinct polysulfide-crosslinked products obtained with CysSSH vs. GSSH. Taken together, these results establish a novel association between the metabolism of polysulfides and the mechanisms for polysulfide sensing inside the cells.

2021年3月25日 · We previously showed that the persulfide-responsive transcriptional factor SqrR acts as a master regulator of sulfide-dependent photosynthesis in proteobacteria. Here, we demonstrated that SqrR also binds heme at a near one-to-one ratio with a binding constant similar to other heme-binding proteins.

2023年2月14日 · 超硫黄分子応答性転写因子SqrR: 超硫黄分子に応答して転写制御を行う転写因子。システイン残基を2つ持ち、超硫黄分子によって、2つのシステイン残基の間で分子内ポリスルフィド架橋構造が形成されることで、転写調節活性が制御される。

2019年8月6日 · Forward genetic analyses identified sqrR as a regulator of the sulphide response. Disruption of sqrR resulted in constitutive high expression of the sqr gene. SqrR represses the expression of proteins related to sulphide metabolism in the absence of sulphide.

2023年2月10日 · SqrR represses a significant portion (45%) of the sulfide-responsive genes in the absence of exogenous sulfide. SqrR forms an intramolecular tetrasulfide bond between two conserved Cys residues when exposed to GSSH, reducing its DNA-binding activity in vitro .