2024年12月25日 · SRRM1 (Serine And Arginine Repetitive Matrix 1) is a Protein Coding gene. Diseases associated with SRRM1 include Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 7.Among its related pathways are Processing of Capped Intron-Containing Pre-mRNA and RHOBTB GTPase Cycle.Gene Ontology (GO) …

SRRM1 human gene location in the UCSC Genome Browser. SRRM1 human gene details in the UCSC Genome Browser This page was last edited on 11 October 2022, at 18:18 (UTC). Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms ...

丝氨酸和精氨酸重复矩阵 1： 启用 RNA 结合活性。预计通过剪接体参与 mRNA 剪接。位于核斑点。催化步骤 2 剪接体的一部分。妊娠糖尿病的生物标志物。 [由基因组资源联盟提供，2022 年 4 月]

srrm1在hcc组织中高表达，与患者的生存和预后有关。 结果 srrm1 在 hcc 肿瘤组织中显着上调，并与 hcc 的进展相关。srrm1的过表达加速了hcc细胞的增殖、迁移和侵袭，并抑制了细胞凋亡，而srrm1的低表达则相反。

Background: To explore the regulatory effect of serine/arginine repetitive matrix 1 (SRRM1) on hepatocellular carcinoma (HCC) and its potential pathway. Methods: SRRM1 level in the tissue was tested by western blot and immunohistochemistry. Cells proliferation, apoptosis, migration, and invasion were tested by EdU, flow cytometry, wound healing assay, and …

2024年5月8日 · The SRRM1 entry clone from DNASU was modified using a Q5 site directed mutagenesis kit (New England Biolabs) to delete the predicted region responsible for nuclear speckle localization as ...

2025年2月8日 · We discovered that two factors, SRRM1 and SF3B1, affect not only cis-SAGe chimeras, but also other types of chimeric RNAs in a genome-wide fashion. two contiguous sequences that independently target SRm160 to nuclear matrix sites at splicing speckled domains: amino acids 300-350 and 351-688;

2022年12月1日 · SRRM1 is splicing coactivator required for the functions of exonic splicing enhancers and for 3-end processing of specific pre-mRNAs (McCracken et al. 2002). In this paper, through cell function experiments, it is found that knockdown of SRRM1 could inhibit cell proliferation, migration and invasion, while up-regulation of SRRM1 exert opposite ...

2025年2月8日 · SRRM1 provided by HGNC Official Full Name serine and arginine repetitive matrix 1 provided by HGNC Primary source HGNC:HGNC:16638 See related Ensembl:ENSG00000133226 MIM:605975; AllianceGenome:HGNC:16638 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage

SRRM1-001: 4011: 904aa: ENSP00000326261.8 . Gene/transcipt that contains an open reading frame (ORF). Protein coding. CCDS255: M0QXG5 Q8IYB3: NM_005839.3: A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt.