ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1
Mar 6, 2024 · We demonstrate that ST3Gal1 plays an important role in modulating tumour immune evasion through the synthesises of sialoglycans with the capacity to engage the …
ST3GAL1 Gene - GeneCards | SIA4A Protein | SIA4A Antibody
Dec 25, 2024 · ST3GAL1 (ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 1) is a Protein Coding gene. Diseases associated with ST3GAL1 include Puerperal Pulmonary Embolism and …
Nat Immunol︱罗切斯特大学团队揭示ST3GAL1和βII-spectrin通路 …
靶向ST3GAL1-βII-spectrin轴可改善T细胞到肿瘤细胞靶点的归巢，提高T细胞免疫治疗的疗效，同时降低与非特异性细胞毒性相关的风险。 为了发现调控CAR-T细胞在体内迁移到非特异性部 …
Sialyltransferase ST3GAL1 promotes cell migration, invasion, …
Oct 30, 2018 · ST3GAL1 is a sialyltransferase that catalyzes the transfer of sialic acid from cytidine monophosphate-sialic acid to galactose-containing substrates and is...
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
ST3GAL1 promotes cell migration, invasion, and TGFB1-induced epithelial-mesenchymal transition and confers paclitaxel resistance in ovarian cancer. Data suggest that GDNF family …
ST3Gal1对血管生成素的唾液酸化促进TGF-β1介导的肿瘤血管生成 …
ST3Gal1是关键的唾液酸转移酶，可将α2,3连接的唾液酸添加至底物并生成核心1 O聚糖结构。 ST3Gal1的上调与乳腺癌患者的预后较差有关。 但是，与肿瘤进展有关的ST3Gal1的蛋白质底 …
ST3GAL1 and βII-spectrin pathways control CAR T cell ... - Nature
Apr 17, 2023 · These findings identify the ST3GAL1–βII-spectrin axis as a major cell-intrinsic program for cancer-targeting CAR T cell migration and as a promising strategy for effective T …
ST3GAL1 and βII-spectrin pathways control CAR T cell ... - PubMed
Here, with a CRISPR-Cas9 pooled library, we performed an in vivo targeted loss-of-function screen and identified ST3 β-galactoside α-2,3-sialyltransferase 1 (ST3GAL1) as a negative …
ST3 β-半乳糖苷 α-2,3-唾液酸转移酶 1（ST3GAL1）基因 | MCE
该基因编码的蛋白质是一种 II 型膜蛋白，可催化唾液酸从 CMP-唾液酸转移到含半乳糖的底物。 编码的蛋白质通常存在于高尔基体中，但可以通过蛋白水解加工成可溶性形式。 编码蛋白质的 …
ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and ...
Nov 17, 2020 · ST3GAL1 induces AXL dimerization and activation that, in turn, promotes melanoma invasion. Our data support a key role of the ST3GAL1-AXL axis as driver of …