
干货分享 | 带你快速入门JAK/STAT signaling pathways信号通路
Janus激酶(JAK)信号转导和转录激活因子(JAK-STAT)途径是一种进化上保守的信号通路,由细胞因子刺激激活,使细胞外信号通过细胞膜传递到细胞核,引起DNA转录的改变,在几个关 …
经典信号通路总结——JAK-STAT信号通路 - 知乎 - 知乎专栏
Jak和Stat是许多调节细胞生长、分化、存活和病原体抵抗信号通路中的关键部分,这一通路涉及到 IL-6 (gp130)受体家族,它帮助调节B细胞的分化,浆细胞生成和急性期反应。
简洁优雅中蕴含着深度—JAK-STAT信号通路 - 知乎
JAK-STAT的名称是由两个基因组成:激酶Janus(Janus kinase)和转录因子STAT(signal transducer and activator of transcription),它们共同参与细胞对各类细胞因子和生长因子的应 …
Chronic activation of JNK JAK/STAT and oxidative stress signalling ...
2017年7月26日 · Here we show that Drosophila wing disc cells carrying functionally unrelated loser mutations (Minute and mahjong) display the common activation of multiple stress …
The JAK/STAT signaling pathway: from bench to clinic
2021年11月26日 · As a fulcrum of many vital cellular processes, the JAK/STAT pathway constitutes a rapid membrane-to-nucleus signaling module and induces the expression of …
JNK and JAK/STAT signalling are required for inducing loss of ... - PubMed
2018年9月1日 · Here, we present evidence for a previously unrecognised function of the cooperative activities of JNK and JAK/STAT signalling pathways in inducing loss of cell fate …
JNK and JAK/STAT signalling are required for inducing loss of cell …
2018年9月1日 · JNK and JAK/STAT signalling cooperates in inducing loss of cell fate specification. Caspase initiator dronc mediates the function of JNK and JAK/STAT in …
JAK-STAT信号通路 - 知乎 - 知乎专栏
STAT为JAK激酶的底物和下游信号分子,英文全称Signal Transducers and Activators of Transcription,其英文名字概述了STAT的两个重要生物学功能,第一是细胞因子信号转导, …
SAPK/JNK 信号级联放大 | Cell Signaling Technology
应激活化蛋白激酶 (sapk)/jun 氨基末端激酶 (jnk) 是 mapk 家族的成员,可由各种不同环境应激、炎症细胞因子、生长因子以及 gpcr 激动剂激活。 应激反应信号经 Rho 家族(Rac、Rho …
JAK/STAT signalling mediates cell survival in response to
2016年8月15日 · Signalling through the Janus kinase/Signal transducers and activators of transcription (JAK/STAT) pathway, which is a potential JNK target, is implicated in promoting …