Stathmin, also known as metablastin and oncoprotein 18 is a protein that in humans is encoded by the STMN1 gene. Stathmin is a highly conserved 17 kDa protein that is crucial for the …

Stathmin 是一种C 端螺旋结构域高度保守 的磷酸化蛋白，通过与α/β微管蛋白结合，促进微 管解聚并抑制微管合成，调控微管的稳定性。 Stathmin 解聚微管的功能受其磷酸化水平的调节， 去 …

At molecular level, stathmin depolymerizes microtubules by either sequestering free tubulin dimers or directly inducing microtubule-catastrophe. A crucial role for stathmin in the control of …

2024年12月25日 · STMN1 (Stathmin 1) is a Protein Coding gene. Diseases associated with STMN1 include Acute Leukemia and Pancreatic Intraductal Papillary-Mucinous Adenoma. …

微管解聚蛋白Stathmin属于微管不稳定调节蛋白家族成员之一,具有促进微管解聚活性.Stathmin通过与细胞内多种蛋白质相互作用,参与细胞生命过程,包括调控细胞周期,细胞运动,细胞内信号转 …

2004年10月1日 · Stathmin is the founding member of a family of proteins that play critically important roles in the regulation of the microtubule cytoskeleton. Stathmin regulates …

2005年11月18日 · We have identified stathmin, an inhibitor of microtubule formation, as highly expressed in the lateral nucleus (LA) of the amygdala as well as in the thalamic and cortical …

2022年3月19日 · Stathmin-1 (STMN1) is a ubiquitous protein that is highly expressed during the development of the nervous system, and its phosphorylation controls microtubule dynamics.

Stathmin (stathmin 1) is a member of the stathmin family of phosphoproteins, which also includes superior cervical ganglia neural-specific 10 protein (SCG10; stathmin 2), SCG10-like protein …

2023年11月23日 · Persistent stathmin-2 loss in adult mice results in pathologies found in ALS, including reduced interneurofilament spacing, axonal caliber collapse that drives tearing within …