The aim of this practical guideline is to support the forensic community with special knowledge on quantitative Nuclear Magnetic Resonance(qNMR) analysis. qNMR has special requirements in comparison to chromatographic methods. The method is very universal and can be used in a variety of forensic applications.

These notes summarise procedures for the acquisition and processing of quantitative 1H, 19F, 31P, and 13C NMR data. It is important to note that quantitative NMR (now referred to commonly as qNMR) is not simply a matter of collecting a 1D spectrum and comparing the integrals.

2024年2月9日 · The process of a qNMR measurement can be divided into 4 steps: Method Planning; Sample Preparation; Data Collection; Data Processing; Method Planning. Selecting a solvent where both the analyte and the internal standard dissolve is necessary but not sufficient.

Steps of quantitative NMR. Experimental parameters. 15 https://www.sigmaaldrich.com/technical-documents/articles/analytical/referencematerials/highperformance- -quantitative-h-1-nmr.html

In this brief brochure, we would like to introduce you to the exciting analytical technique of quantitative nuclear magnetic resonance spectrometry (qNMR). In 2009, Sigma-Aldrich …

2023年12月18日 · 定量核磁技术（Quantitative Nuclear Magnetic，简称QNMR)主要是基于1H-NMR，待测化合物1H-NMR谱上各信号峰强度之比等于相应的质子数之比，确定氢的积分值与其摩尔浓度成正比，定量核磁方法分为相对定量法和绝对定量法。

2020年1月14日 · The advanced approaches described in this review allow the application of qNMR to a broad range of systems and extend the molecular weight range of analytes that may be applicable to qNMR. These approaches can remove potential systematic errors in qNMR through interference of overlapping peaks and improve its trueness, thus expanding its ...

2012年5月1日 · We provide the basic concepts of quantitative NMR (qNMR), a brief description of important acquisition and processing parameters responsible for obtaining high-quality, reproducible NMR spectra...

The best practice of a qNMR procedure consists of at least six steps: instrument qualification, sample preparation, method development, method validation, qNMR measurement, and data processing and analysis. Finding and following the best practices for a qNMR procedure can save a lot of time and trouble and improve the outcomes. 4.1 NMR Instrument

2020年1月17日 · A qNMR experiment is very easy to perform, however, the setting of the respective parameters is the most crucial point. The guideline explains step-by-step how to proceed with the sample preparation and the NMR analysis, which is universal for a variety of forensic and other applications.