SU16f is a potent and selective PDGFRβ inhibitor with IC 50 s of 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively. Neutralization of PDGFRβ receptor by SU16f …

su16f (su 16f )是细胞可渗透的吲哚酮化合物，是有效的pdgfrβ选择性抑制剂，ic 50 为10 nm。 SU16f 作用于 PDGFR1/2 的 IC 50 分别为 140 nM 和 2.29 μM 。 产品性质

脊髓原位注射外源性PDGFB或PDGFD用于特异性激活未损伤脊髓中的PDGFRβ通路，而鞘内注射SU16f用于特异性阻断未损伤或损伤脊髓中的PDGFRβ通路。 进行免疫荧光染色以探 …

SU 16f is a potent and selective platelet-derived growth factor receptor β (PDGFR β) inhibitor (IC 50 = 10 nM) that displays > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, …

SU 16f is a potent and selective platelet-derived growth factor receptor β (PDGFR β) inhibitor (IC 50 = 10 nM) that displays > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, …

SU16f is a potent and selective PDGFRβ inhibitor with IC50 s of 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively [1]. Neutralization of PDGFRβ receptor by SU16f …

2022年4月16日 · Our study demonstrates that activation of PDGFRβ pathway can directly induce fibrotic scar formation, and specific blocking of this pathway would contribute to the treatment …

2022年4月16日 · SU16f is a potent and highly selective PDGFRβ inhibitor that displays > 14-fold, > 229-fold and > 10,000-fold selectivity over VEGFR2, FGFR1 and EGFR, respectively, and …

SU16f 是一种强效的选择性 PDGFRβ 抑制剂，对 PDGFRβ、PDGFR1 和 PDGFR2 的 IC50 分别为 10 nM、140 nM 和 2.29 μM。 用 SU16f 中和 PDGFRβ 受体可阻断 GC-MSCs（胃癌间充 …