Sulfadiazine is a sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid. One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

Sulfadiazine is a sulfonamide antibacterial agent used in the therapy of mild-to-moderate infections due to sensitive organisms. Sulfadiazine, like other sulfonamides, is a well known cause of clinically apparent, idiosyncratic liver injury.

Sulfadiazine is an antibiotic. [1] Used together with pyrimethamine, a dihydrofolate reductase inhibitor, it is the treatment of choice for toxoplasmosis, which is caused by a protozoan parasite. [3] It is a second-line treatment for otitis media, prophylaxis of rheumatic fever, chancroid, chlamydia, and infections by Haemophilus influenzae. [1]

2023年1月22日 · Silver sulfadiazine is a medication used to prevent, manage, and treat burn wound infections. It is a heavy metal topical agent with antibacterial properties. This activity reviews the indications, action, and contraindications for silver sulfadiazine as a valuable agent in preventing infection in burn patients.

Includes SulfADIAZINE indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.

Sulfadiazine mimics para-aminobenzoic acid (PABA), a substrate that is crucial for the production of dihydropteroate, a precursor in the folic acid synthesis pathway. By structurally resembling PABA, Sulfadiazine competes with it for binding to the enzyme dihydropteroate synthase .

Sulfadiazine is a drug that is used to treat various infections caused by bacteria such as streptococci, gonococci, pneumococci, staphylococci, and colon bacillus. It is also used for pneumonia, cerebral meningitis, and other infectious diseases, and …

sulfadiazine increases effects of insulin NPH by unspecified interaction mechanism. Use Caution/Monitor. Concomitant use of insulin and sulfonamide antibiotics may require...

Mechanism of Action. Inhibits bacterial synthesis of folic acid; Comments See Also. Antibiotics; References

MoA: Disrupts folic acid synthesis which impacts bacterial replication. Indications: Gram(+,-) Bacteria, UTI, HIV-associated Pneumonia, Staphylococcus Infections, MRSA. Contraindications: Pregnant Women, Infants. Side Effects: Headache, Dizziness. Drug Interactions: Celebrex, Alcohol. Nursing Implications: