Sulfadimidine or sulfamethazine is a sulfonamide antibacterial. There are non-standardized a abbreviations for it as "sulfadimidine" (abbreviated SDI[1][2] and more commonly but less reliably b SDD[3][4]) and as "sulfamethazine" (abbreviated SMT[5][6] and more commonly but less reliably c SMZ[7][8]).

磺胺二甲嘧啶，是一种有机化合物，化学式为C12H14N4O2S，是一种广谱抑菌剂，在结构上类似对氨基苯甲酸（PABA），可与PABA竞争性作用于细菌体内的二叶酸合成酶，从而阻止PABA作为原料合成细菌所需要叶酸的过程，减少了具有代谢活性的四氢叶酸的量，而后者则是细菌合成嘌吟、胸腺嘧啶核苷和脱氧核糖核酸 (DNA)的必需物质，因此抑制了细菌的生长繁殖。 2017年10月27日，世界卫生组织国际癌症研究机构公布的致癌物清单初步整理参考，磺胺二甲嘧啶在3类 …

2025年1月7日 · Sulfadimidine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfadimidine is bacteriostatic in nature.

Sulfamethazine is a sulfonamide consisting of pyrimidine with methyl substituents at the 4- and 6-positions and a 4-aminobenzenesulfonamido group at the 2-position.

Sulfonamides (sulfa antibiotics) are a class of synthetic molecules that share a common p-aminobenzenesulfonamide moiety, which is needed for the antibacterial activity. Representatives of this class are sulfadoxine, sulfadiazine, sulfaquinoxaline and sulfamethazine, which is, perhaps, the most extensively used sulfonamide.

2024年11月8日 · Sulfadimidine is prescribed to treat urinary tract infections, prostatitis (infection of the prostate gland) and respiratory tract infections caused by bacteria. It is capable of inhibiting the...

磺胺二甲嘧啶钠（英文名称：Sulfadimidine Sodium Injection），本品为白色或乳白色结晶性粉末，无臭或几乎无臭，易溶于水，略溶于乙醇。 是一种抗菌磺胺药，诱导CYP3A4表达，以及通过N-乙酰转移酶乙酰化。

A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides. DrugCentral is online drug information resource created and maintained by Division of Translational Informatics at University of New Mexico.

Overview Primary Characterstics Indications Pharmacokinetics Contraindications Drug Interactions Side Effects Dosage High Risk Groups Warning / Precautions Storage Conditions Interference in Pathology Brands of Sulfadimidine Manufacturers of Sulfadimidine

葡萄狀球菌、鏈鎖球菌、肺炎雙球菌、大腸菌、赤痢菌及綠膿菌引起感染症。 一般成人初劑量為6-8錠，每4-6小時服用第二錠。 與對氨基苯甲酸（PABA）競爭性結合二氫葉酸合成酶（DHPS），抑制細菌葉酸合成。 可以抑制細菌製造葉酸，葉酸是細菌製造DNA之必須，會使其無法複製、死亡。 使用本劑偶有食慾不振、噁心、嘔吐、下痢等胃腸障害。 如出現發疹等過敏現象，終止使用本劑。 偶有食慾不振、噁心、嘔吐、下痢等胃腸到症狀。 如出現過敏現象，請停 …