2024年12月25日 · SUPT16H (SPT16 Homolog, Facilitates Chromatin Remodeling Subunit) is a Protein Coding gene. Diseases associated with SUPT16H include Neurodevelopmental …

FACT complex subunit SPT16 is a protein that in humans is encoded by the SUPT16H gene. [5][6][7] Transcription of protein-coding genes can be reconstituted on naked DNA with only …

Our findings implicate the gene <i>SUPT16H</i> in a novel disorder characterised by neurodevelopmental deficits and CC anomalies.

SUPT16H encodes the large subunit of the FA cilitate C hromatin T ranscription (FACT) complex, which functions as a nucleosome organizer during transcription. We identified two individuals …

2025年2月9日 · The fly homolog of SUPT16H, a gene associated with neurodevelopmental disorders, is required in a cell-autonomous fashion for cell survival. Structural basis for H2A …

2021年4月21日 · FACT subunit SUPT16H undergoes protein acetylation at K674 of MD domain, catalyzed by TIP60, which is recognized by BRD4. Such SUPT16H-BRD4 interaction prevents …

The SUPT16H gene encodes a component of the FACT (facilitates chromatin transcription) complex, a chromatin-specific factor required for transcription elongation as well as for DNA …

2024年2月4日 · HIV-1 Rev interacting protein, suppressor of Ty 16 homolog (SUPT16H), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa …

The SUPT16H gene encodes for a component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that …

2012年5月9日 · Clinical resource with information about SUPT16H, Neurodevelopmental disorder with dysmorphic facies and thin corpus callosum, and available tests. There are links to …