2019年6月5日 · Here we introduce a rapid, versatile, and scalable method, eFLASH, that enables complete and uniform labeling of organ-scale tissue within one day. eFLASH dynamically modulates chemical transport and reaction kinetics to establish system-wide uniform labeling conditions throughout the day-long labeling period.

2022年2月17日 · We established interactions of Tau with presynaptic vesicle proteins during activity-dependent Tau secretion and mapped the Tau-binding sites to the cytosolic domains of integral synaptic vesicle proteins.

DL Swaney, GC McAlister, M Wirtala, JC Schwartz, JEP Syka, JJ Coon. Analytical chemistry 79 (2), 477-485, 2007. 439: ... DL Swaney, TS Chang, M Moritz, C Konrad, ... Cell 185 (4), 712-728. e14, 2022. 213: 2022: Dual-pressure linear ion trap mass spectrometer improving the analysis of complex protein mixtures.

We established interactions of Tau with presynaptic vesicle proteins during activity-dependent Tau secretion and mapped the Tau-binding sites to the cytosolic domains of integral synaptic vesicle proteins.

Justin Swaney*, Lee Kamentsky*, Nicholas B Evans, Katherine Xie, Young-Gyun Park, Gabrielle Drummond, Dae Hee Yun, Kwanghun Chung †. "Scalable image processing techniques for quantitative analysis of volumetric biological images from light-sheet microscopy", bioRxiv, 2019, DOI:10.1101/576595.

My interest is in using proteomics approaches to advance our understanding of both basic and disease biology. Of particular interest to me is the study of protein-protein interactions/complexes and post-translational modification signaling in the context of infection and neurodegeneration.

Here we introduce a rapid, versatile, and scalable method, eFLASH, that enables complete and uniform labeling of organ-scale tissue within one day. eFLASH dynamically modulates chemical transport and reaction kinetics to establish system-wide uniform labeling conditions throughout the day-long labeling period.

My interest is in using proteomics approaches to advance our understanding of both basic and disease biology. Of particular interest to me is the study of protein-protein interactions/complexes and post-translational modification signaling in the context of infection and neurodegeneration.

These results are interpreted in terms of protein insertion at lattice defects arising from the presence of phospholipid clusters undergoing the phase transition; these clusters are derived from the cooperative and simultaneous melting of a number of molecules, the cooperativity being dependent upon the nature of the phospholIPid. Studies of the recombination of apolipoprotein A …

Tracy TE, Madero-Pérez J, Swaney DL, Chang TS, Moritz M, Konrad C, Ward ME, Stevenson E, Hüttenhain R, Kauwe G, Mercedes M, Sweetland-Martin L, Chen X, Mok SA, Wong ...