2024年12月25日 · SYK (Spleen Associated Tyrosine Kinase) is a Protein Coding gene. Diseases associated with SYK include Immunodeficiency 82 With Systemic Inflammation and Arthritis. …

Tyrosine-protein kinase SYK, also known as spleen tyrosine kinase, is an enzyme which in humans is encoded by the SYK gene. [5][6][7] SYK, along with ZAP70, is a member of the Syk …

2010年5月14日 · Spleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase that has long been thought to exclusively mediate signalling by receptors of the adaptive immune response …

syk的细胞生物学功能主要为抑制细胞增殖、影响细胞分化、抑制肿瘤细胞的成瘤能力、影响某些细胞因子的分泌等。 它在免疫细胞中广泛表达，与B细胞受体和 Fcγ受体 等表面受体直接相 …

2021年3月29日 · Spleen tyrosine kinase (SYK) is a critical immune signaling molecule and therapeutic target. We identified damaging monoallelic SYK variants in six patients with …

Spleen tyrosine kinase (SYK) is an enigmatic protein tyrosine kinase, and involved in signal transduction related with lots of cellular processes. It’s highly expressed in the cells of …

2025年1月1日 · Spleen tyrosine kinase (SYK), a non-receptor tyrosine kinase, is predominantly expressed in B cells, T cells and macrophages, playing a critical role in immune responses by …

2025年2月8日 · Title: Syk protein inhibitors treatment for the allergic symptoms associated with hyper immunoglobulin E syndromes: A focused on a computational approach. Syk-dependent …

Seven novel SYK gene SNPs were identified in breast cancer patients. Syk might down-regulate the expression of VEGF-C by inhibiting the activity of NFkappaB, which thus suppresses …

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated …