A corticosteroid taken by mouth or given by intramuscular injection is often called a systemic steroid. Systemic steroids are synthetic derivatives of the natural steroid, cortisol, produced by the adrenal glands, and have profound anti-inflammatory effects. Systemic (cortico)steroids are also called glucocorticoids or cortisones. They include:

Patients prescribed systemic steroids for skin diseases should be carefully advised of potential risks and adverse effects. Acute dermatoses Systemic steroids may be used to treat acute severe skin diseases such as plant contact allergy, autosensitisation dermatitis, flares of atopic dermatitis, Sweet disease and drug hypersensitivity syndrome.

2017年4月4日 · Systemic corticosteroids can cause an increased risk of gastrointestinal events, such as gastritis, peptic ulcer, and gastrointestinal haemorrhage [1,4]. Assessment Assess the patient’s history of risk factors for peptic ulcer [5]; these include:

Systemic corticosteroids (eg, prednisone) are generally used in the more severe cases of drug hypersensitivity syndrome with significant exfoliative dermatitis, pneumonitis, and/or hepatitis. However, the benefits of corticosteroids are unknown as controlled clinical trials are lacking.

Adrenal Suppression Associated with the Use of Topical Corticosteroids. Medsafe. Prescriber Update 38(4): 52–3. December 2017. On DermNet. Systemic steroids; Intralesional steroids; Topical corticosteroid contact allergy ; Topical corticosteroid withdrawal; Allergies explained; Occupational dermatitis among construction workers

Dixon WG, Kezouh A, Bernatsky S, Suissa S. The influence of systemic glucocorticoid therapy upon the risk of non-serious infection in older patients with rheumatoid arthritis: a nested case-control study. Ann Rheum Dis 2011; 70: 956. DOI: 10.1136/ard.2010.144741. PubMed; Plotkin SA. Correlates of protection induced by vaccination.

Systemic steroids; Prophylactic treatments for dermatology patients on systemic corticosteroids; Other websites. Cushing Syndrome — Medscape Drugs & Diseases; Glucocorticoid Therapy and Cushing Syndrome — Medscape Drugs & Diseases; Cushing syndrome — Endocrine web . Books about skin diseases. Books about the skin; Dermatology Made Easy ...

Systemic corticosteroids; Surgery. Acne conglobata. Acne conglobata is an uncommon and unpleasant form of nodulocystic acne in which there are interconnecting abscesses and sinuses, which result in unsightly hypertrophic (thick) and atrophic (thin) acne scars. There are groups of large macrocomedones and cysts that are filled with smelly pus.

2021年7月21日 · Systemic corticosteroids >are the mainstay of medical treatment for controlling the disease, usually in the form of moderate to high doses of oral prednisone or prednisolone, or as pulsed intravenous methylprednisolone. Since their use, many deaths from pemphigus vulgaris have been prevented (the mortality rate dropped from 99% to 5–15%).

Systemic steroids. A short course of systemic corticosteroids can be very useful to quickly control a flare and to provide temporary respite, especially for important occasions such as a wedding. Immunosuppressive and anti-inflammatory agents. Long-term control of severe disease may require an immunosuppressive or anti-inflammatory agent such as: