Translocation-specific polymerase chain reaction (PCR) detects de novo t(11;22)s in sperm from normal healthy males. We established a t(11;22)-specific PCR system utilizing sequence data …

The t(11;22)(q23;q11) translocation is the most common recurrent balanced translocation described in humans. Carriers are phenotypically normal and often go undetected until …

2000年6月12日 · The t(11;22) is the most common recurrent non-Robertsonian constitutional translocation in humans, having been reported in more than 160 unrelated families. Balanced …

回顾性分析临床上t(11；22)相互易位核型分布及其携带者的临床特征，为t(11；22)相互易位核型携带者提供遗传咨询和合理的辅助生育意见。 方法 分析2014年1月-2019年9月临床上t(11；22) …

2022年12月19日 · 2004年，Emanuel 综合征是以费城细胞遗传学家贝弗利·伊曼纽尔博士 (Dr Beverly Emanuel)的名字命名的，又称额外der (22)t (11;22)染色体综合征。 Emanuel 综合征发 …

The constitutional t (11;22) (q23;q11) is the most common recurrent non-Robertsonian translocation in humans. The breakpoint sequences of both chromosomes are characterized …

2010年2月24日 · Here, we have studied eight cases of de novo t (11;22) to determine the parental origin of the translocation using the polymorphisms on the relevant PATRRs. All of the eight …

The constitutional t(11;22) translocation is the only known recurrent non-Robertsonian translocation in humans. Offspring are susceptible to der(22) syndrome, a severe congenital …

The t(11;22)(q23;q11) translocation is the most common recurrent balanced translocation described in humans. Carriers are phenotypically normal and often go undetected until …

Translocation t(11;22)(q23;q11) is the most common constitutional reciprocal translocation in man. Balanced carriers are phenotypically normal, except for decreased fertility, an increased …