Type 1 diabetes (T1D) results from a T cell dependent, autoimmune destruction of insulin producing beta cells in pancreatic islets of Langerhans, which results in insulin deficiency despite...

2012年11月5日 · Mara Bonelli remembers life without diabetes and she wants her daughter Claire to have that life back. Claire was diagnosed with T1D at age seven in 1997, and since then it has been non-stop management of the disease. From the beginning, the family has participated in the Walk to Cure Diabetes as way to connect…

免疫治疗的现状 靶向T细胞 目前，针对T1D走在最前列的免疫治疗药物是 替利珠单抗 (teplizumab)，一种人源化的Fc受体非结合性抗CD3ε单抗（mAb），目前正在开发用于治疗2期和3期T1D患者。一项针对处于3期T1D患者的临床3期试验结果显示，替利珠单抗虽然未能取得预期 ...

2025年3月28日 · Mara Kinney, TrialNet Manager at the Barbara Davis Center, says Brenda has participants who adore her and even send her photos and videos regarding their involvement in TrialNet studies. Recently, the mother of a participant in the HCQ Study sent Brenda a video of her son taking the study drug to show how easy it is.

2013年6月25日 · In this review article, we discuss the central role of immune responses in the patho-physiology and complications of type 1 and 2 diabetes, and provide evidence that regulation of these responses, particularly through the action of regulatory T cells, may be a possible therapeutic avenue for the treatment of these disease and their respective co...

2025年1月7日 · 1型糖尿病（t1d）作为一种影响儿童、青少年以及成人健康的重大慢性代谢性疾病 ，长期以来备受全球医疗 界的广泛关注。过去的一年，t1d筛查、预测、诊断、治疗新技术及新方法方面均取得了诸多重要进展。

2021年8月29日 · 目前，针对T1D走在最前列的免疫治疗药物是替利珠单抗 (teplizumab)，一种人源化的Fc受体非结合性抗CD3ε单抗（mAb），目前正在开发用于治疗2期和3期T1D患者。

2020年12月2日 · Feeling alone is a common reaction to being diagnosed with Type 1 Diabetes (T1D), but not for the Ballew girls of Portland, OR. Mara Stine and Troy Ballew have three daughters: Ayla, June, and Tessa. In 2013, their middle daughter June was diagnosed with T1D at …

2024年11月9日 · t1d是一种由t细胞介导的自身免疫性疾病，主要表现为胰岛β细胞的破坏。文章揭示了tigit+ treg-tgf-β-cd226+cd8+ t细胞的相互作用在t1d进展和缓解中的关键作用。研究发现，ti

EASE T1d - United States and Internationally, brings Education, Awareness, Support, & Empowerment about Type 1 Diabetes. EASE T1d is a great place for information and resources. EASE T1d is a 501 (c) (3) non-profit that relies upon generous donations.