2024年12月25日 · TAF1 (TATA-Box Binding Protein Associated Factor 1) is a Protein Coding gene. Diseases associated with TAF1 include Dystonia 3, Torsion, X-Linked and Intellectual …

A mutation in TAF1 was identified that contributes to a phenotype with severe intellectual disability (ID), a characteristic intergluteal crease, and distinctive facial features, including a broad, …

2019年7月24日 · We investigated the role of TAF1 and its association to neurodevelopment by creating the first complete knockout model of the TAF1 orthologue in zebrafish. A crucial …

2019年7月24日 · The TATA-box binding protein associated factor 1 (TAF1) protein is a key unit of the transcription factor II D complex that serves a vital function during transcription initiation. …

Mutations in this gene result in Dystonia 3, torsion, X-linked, a dystonia-parkinsonism disorder. Alternative splicing of this gene results in multiple transcript variants. This gene is part of a …

TFIID 由 TATA 结合蛋白 (TBP) 和一组称为 TBP 相关因子或 TAF 的进化保守蛋白组成。 TAF 可能参与基础转录，充当共激活因子，在启动子识别中发挥作用或修饰一般转录因子 (GTF) 以促 …

Currently, TAF1 has been identified as the causative gene of X-linked dystonia-parkinsonism and X-linked mental retardation. What′s more, a series of functional analysis have demonstrated …

taf1是x连锁肌张力障碍-帕金森综合征和x连锁的精神发育迟滞等疾病的致病基因，因其在转录过程中占有重要地位，taf1已成为多种疾病发生发展机制研究中的关注热点。

2024年1月7日 · TAF1 bromodomain inhibition as a candidate epigenetic driver of congenital heart disease. TAF1 promotes NSCLC cell epithelial-mesenchymal transition by transcriptionally …

We describe an X-linked genetic syndrome associated with mutations in TAF1 and manifesting with global developmental delay, intellectual disability (ID), characteristic facial …