TBR1 - Wikipedia
Tbr1 is a protein, called a transcription factor, that binds to DNA and regulates the transcription of genes into mRNA. It is expressed in postmitotic projection neurons and is critical for normal …
TBR1 Gene - GeneCards | TBR1 Protein | TBR1 Antibody
2024年12月25日 · TBR1 (T-Box Brain Transcription Factor 1) is a Protein Coding gene. Diseases associated with TBR1 include Intellectual Developmental Disorder With Autism And Speech …
各神经元的Marker - 丁香园论坛
t 盒脑蛋白 1 (tbr1) 是脊椎动物胚胎发育过程中的一个重要转录因子。 作为 T 盒转录因子家族的一员， TBR1 在有丝分裂后期谷氨酸能投射神经元中表达。
Brain-specific transcriptional regulator T-brain-1 controls brain ...
2015年11月2日 · In this review, we summarize the physiological functions of TBR1 and the currently understood mechanisms by which TBR1 mutations cause ASDs. Based on the data …
Tbr1 Regulates Differentiation of the Preplate and Layer 6
2001年2月1日 · The high expression of Tbr1 in the preplate and cortical plate suggested that Tbr1 might play an important role in cortical development. To investigate this hypothesis, we …
Characterization of the TBR1 interactome: variants associated with ...
2022年12月29日 · TBR1 is a neuron-specific transcription factor involved in brain development and implicated in a neurodevelopmental disorder (NDD) combining features of autism …
Essential roles of Tbr1 in the formation and maintenance of the ...
Here, we demonstrate that T-box transcription factor T-brain 1 (Tbr1) is expressed in 2 groups of morphologically and functionally distinct RGCs: the orientation-selective J-RGCs and a group …
Tbr1影响大脑皮质发育及细胞分化与迁移 - bjmu.edu.cn
As a marker of newborn neuron, Tbr1 is involved in the cortical lamination and affects the processes of cell migration and neural differentiation. Key words: Cortical lamination, …
文献解读|Nature（58.39）：全小鼠大脑中细胞类型的高分辨率转 …
2023年12月13日 · 皮层谷氨酸能特异性模块包括Tbr1和Satb2，它们在不同亚类中也表现出差异表达。 直接早期基因Egr3和Nr4a1在大脑皮层谷氨酸能神经元中高表达，而Fos和Fosb表达更为 …
Brain-specific transcriptional regulator T-brain-1 controls brain ...
2015年11月3日 · T-brain-1 (TBR1) is a brain-specific T-box transcription factor. In 1995, Tbr1 was first identified from a subtractive hybridization that compared mouse embryonic and adult …