锝 [99mTc]亚甲基二膦酸盐注射液，适应症为主要用于全身或局部骨显像，诊断骨关节疾病、原发或转移性骨肿瘤病等。 本品为无色澄明液体。 主要用于全身或局部骨显像，诊断骨关节疾病、原发或转移性骨肿瘤病等。 成人静脉注射370～740MBq (10～20mCi) 99m Tc-MDP，2～3小时后显像，注射后嘱病人多饮水以加速清除非骨组织的显像剂。 取适合的体位检查，检查时应包括相对称的健康侧，以便与患侧作比较。 正常骨浓聚显像剂的量各部位不同，一般扁平骨较长骨显像 …

2020年10月22日 · Technetium-99m (99mTc) is an FDA-approved radionuclide agent for diagnostic imaging across various human organs, encompassing critical areas such as the brain, lungs, heart, and more. Following systemic administration, 99mTc is …

Technetium (99m Tc) medronic acid is a pharmaceutical product used in nuclear medicine to localize bone metastases [1] as well as other diseases that can alter the natural turn-over in the bone by bone scintigraphy.

2022年1月6日 · Technetium 99m-methyl diphosphonate (99mTc MDP) is a radiotracer used in nuclear medicine especially for bone scintigraphy. Any disease process which results in extracellular fluid expansion will lead to accumulation of this tracer.

2007年3月29日 · Imaging with 99m Tc-methylene diphosphonate (99m Tc-MDP) is the initial method of choice to detect skeletal metastases in cancer patients (9). For SPECT of the bone, metastable technetium (99m Tc) is tagged onto a phosphonate compound such as MDP to generate 99m Tc-MDP, which selectively concentrates in the bone.

99m Tc-MDP是目前公认的较理想的骨显像剂。 通过化学吸附结合于骨骼的无机成分中的羟基磷灰石结晶(hydroxypatitecrystal)表面，此外骨内未成熟的胶原，也对 99m Tc-MDP有较高的亲和力。

Quantitative measurement of bone using 99m Tc-methylene diphosphonate (99m Tc-MDP) provides global or local information of skeletal metabolism or transformation. In this paper, we make a brief review on the quantitative measurement of bone using 99m Tc-MDP and expect to provide guidance for clinical diagnosis and treatment.

2018年9月1日 · In this article, we will review the normal biodistribution of Tc-99m MDP on bone scans, and provide examples of extraskeletal Tc-99m MDP localization owing to both benign and malignant conditions. These include disturbances in calcium metabolism, soft-tissue damage such as in setting of physical trauma, urinary tract anomalies, and errors in ...

Technetium-99m hydroxymethylene diphosphonate (Tc-99m HMDP) is a new diphosphonate skeletal imaging agent. Animal studies show that Tc-99m HMDP has a higher uptake on bone and a more rapid clearance from the blood than any of the three technetium-labeled bone imaging agents in current use: Tc-99m methylene diphosphonate (MDP), Tc-99m (1 ...

Technetium 99m-methyl diphosphonate (Tc-99m MDP) is an ideal bone scintigraphy agent due to its high bone-to-soft tissue uptake, rapid blood clearance, and good in-vivo stability. [1, 2, 3] Tc-99m MDP is chemisorbed on the bone tissue based on the osteoblastic activity of bony remodeling and blood flow to the tissue.