急性胆红素脑病是基于临床的诊断，主要见于TSB>342 μmol/L (20 mg/dl)和 (或)上升速度>8.5 μmol/L (0.5 mg/dl)、>35周的新生儿。 胆红素神经毒性所致的急性中枢神经系统损害，早期表现为肌张力减低、嗜睡、尖声哭、吸吮差，而后出现肌张力增高，角弓反张，激惹，发热，惊厥，严重者可致死亡。 低出生体重儿发生胆红素脑病时通常缺乏典型症状，而表现为呼吸暂停、循环呼吸功能急剧恶化等，不易诊断。 通常足月儿发生胆红素脑病的TSB峰值在427 μmol/L (25 mg/dl)以 …

2014年6月1日 · The American Academy of Pediatrics recommends universal screening with TSB or transcutaneous bilirubin (TcB) levels, or targeted screening based on risk factors. 5 Universal TSB/TcB...

Measure TcB or TSB; Obtain TSB if: TcB level within 3 mg/dL of Phototherapy Threshold; TcB > 15 mg/dL; Determine the time of bilirubin recheck; Refer to ED as indicated

Transcutaneous bilirubin (TcB) measurement is a non‐invasive method for measuring serum bilirubin level (Dai 1997). Transcutaneous bilirubinometry works by directing light into the skin and measuring the intensity of the wavelength of light that is returned (Boo 2007).

Introduction: Transcutaneous bilirubin (TcB) measurement offers a noninvasive approach for bilirubin screening; however, its accuracy in preterm infants is unclear. This study determined the agreement between TcB and total serum bilirubin (TSB) among preterm infants.

Our study demonstrates a strong linear relationship and good diagnostic accuracy of TcB values compared to TSB values. To conclude, TcB measured at the forehead or sternum is a good alternative as a non-invasive screening tool for non-severe hyperbilirubinemia in Malay neonates.

2023年11月22日 · Transcutaneous bilirubinometry (TcB) is an increasingly applied noninvasive, painless, easily reproducible, and cost-effective point-of-care alternative to estimate TSB. 3 – 5 TcB measures cutaneous bilirubin by directing light into the skin and measuring the intensity of reflecting specific wavelengths. 6.

一旦发现生后24 h内出现黄疸，应尽早完善TcB或TSB检测。（综合证据质量等级X，强烈推荐） 尽管生后24 h内出现黄疸的病因可能不明，但最大可能是溶血。漏诊严重溶血所致黄疸的后果很严重，提示早期TSB与TcB检测非常重要。

2016年8月17日 · tsb 是诊断新生儿黄疸的金标准，为抽取血液的有创检查。tcb 测量广泛应用后，tsb 现多推荐用于 tcb 水平高于光疗阈值后的确诊检查，其敏感性和特异性均接近 100%。

光疗过程中密切监测胆红素水平，6~12 h监测1次TCB，严重高胆红素血症者4~6 h复查TSB并评估光疗效果。停光疗指征为TCB或TSB低于光疗阈值50 μmol/L（3 mg/dl）。