TCF4 - Wikipedia
TCF4 is primarily involved in neurological development of the fetus during pregnancy by initiating neural differentiation by binding to DNA. It is found in the central nervous system, somites, and …
TCF4 Gene - GeneCards | ITF2 Protein | ITF2 Antibody
2024年12月25日 · TCF4 (Transcription Factor 4) is a Protein Coding gene. Diseases associated with TCF4 include Pitt-Hopkins Syndrome and Corneal Dystrophy, Fuchs Endothelial, 3. …
TCF4 gene - MedlinePlus
The TCF4 gene provides instructions for making a protein that attaches (binds) to specific regions of DNA and helps control the activity of many other genes. On the basis of this action, the …
Transcription factor TCF4: structure, function, and associated
This review focuses on the TCF4 gene that encodes a transcription factor crucial for nervous system development and functioning. Pathogenic variants in this gene have been linked to a …
Transcription factor TCF4: structure, function, and associated …
TCF4 encodes a transcription factor containing a basic helix-loop-helix structural motif (bHLH). The proteins of this group contain a DNAbinding domain and can regulate gene expression, …
转录因子 4（TCF4）基因 | MCE - MCE-生物活性分子大师
编码的蛋白质识别 Ephrussi 盒 ('E-box') 结合位点 ('CANNTG') - 一个在免疫球蛋白增强剂中首次发现的基序。 该基因广泛表达，可能在神经系统发育中发挥重要作用。 该基因的缺陷是皮特-霍 …
Transcription factor 4 and its association with psychiatric disorders
2021年1月5日 · The human transcription factor 4 gene (TCF4) encodes a helix–loop–helix transcription factor widely expressed throughout the body and during neural development.
Cell | 空间多组学揭示TCF4依赖性基因调控网络赋予黑色素瘤对免 …
tcf4是mes特征的核心调控因子，也是黑色素细胞和抗原递呈转录程序的抑制因子，是这一特征的枢纽，使用溴域抑制剂在基因上或药理学上靶向tcf4可增加mes细胞的免疫原性和对icb及靶向 …
TCF4 transcription factor 4 - NIH Genetic Testing Registry (GTR)
2025年2月8日 · Clinical resource with information about TCF4, A comprehensive family-based replication study of schizophrenia genes., Biological insights from 108 schizophrenia …
Psychiatric risk gene Transcription Factor 4 (TCF4) regulates the ...
2023年9月28日 · Transcription factor 4 (TCF4) is a basic helix-loop-helix transcription factor that is implicated in a variety of psychiatric disorders including autism spectrum disorder...