2020年6月16日 · FlyTF is a database of computationally predicted and/or experimentally verified site-specific transcription factors (TFs) in the fruit fly Drosophila melanogaster. It covers the DNA-binding characteristics of the proteins and a more fine-grained annotation of both DNA binding and regulatory properties.

TFLink gateway uniquely provides comprehensive and highly accurate information on transcription factor - target gene interactions, nucleotide sequences and genomic locations of transcription factor binding sites for human and six model organisms: mouse (Mus musculus), rat (Rattus norvegicus), zebrafish (Danio rerio), fruit fly (Drosophila ...

Computational analysis of evolutionarily-conserved TF DNA binding sites is commonly used to predict and analyze CRMs within genomes. These approaches have been limited by the relatively small numbers of TFs with high quality data describing their DNA binding specificity.

2015年7月15日 · FlyTF is a database of computationally predicted and/or experimentally verified site-specific transcription factors (TFs) in the fruit fly Drosophila melanogaster. FlyTF: improved annotation and enhanced functionality of the Drosophila transcription factor …

2019年4月16日 · In brief, TF combinations were generated and tested by crossing pairs of GMR-Gal4;TF-VN and GMR-Gal4;TF-VC fly strains, leading to co-expression of the fusion proteins in the eye tissue. The crosses were kept at 21°C until dissection to saturate protein expression levels, which is a critical parameter for maximizing the specificity of BiFC.

Although the published sequence of the fly genome has been available for many years now, it is still difficult to name the number of exact number site-specific transcription factors (TFs). The major obstacles in counting those factors lie within the experimental and computational identification of TFs, as well as in the lack of a unifying ...

2006年4月13日 · Summary: We present a manually annotated catalogue of site-specific transcription factors (TFs) in the fruit fly Drosophila melanogaster. These were identified from a list of candidate proteins with transcription-related Gene Ontology (Go) annotation as well as structural DNA-binding domain assignments.

2006年6月15日 · We propose a set of 753 TFs in the fruit fly, of which 23 are confident novel predictions of this function for previously uncharacterized proteins. We present a manually annotated catalogue of site-specific transcription factors (TFs) in …

Welcome to the FlyTF gateway. We are currently in the process of moving to a new server. Until this move has completed, you may choose one of the following... FlyTF v2: Enter or retrieve Help for FlyTF v2. FlyTF v1: Enter.

This database contains information on the manual curation of 1052 FlyBase identifiers, which are putative site-specific transcription factors, based on FlyBase/Gene Ontology annotation or the DBD Transcription Factor Database.. The new release (v2) of FlyTF is available here: FlyTFMine.